Michael Freiman ‘03
The Effect of Nasal CPAP on INtranasa Geometry
Introduction
Nasal continuous positive airway pressure (nCPAP) is generally accepted as the first line treatment of obstructive sleep apnea (OSA) and its success is largely dependent on patient compliance. Sinonasal complaints, often nasal congestion and nasal airway obstruction (NAO), are some of the most frequent side-effects which lead to non-compliance. We hypothesize that nCPAP alters the intranasal geometry, which may lead to the sinonasal complaints associated with its use.
Methods
A prospective, doubly repeated measures design will be used on patients referred to The University of Wisconsin Sleep Disorders Center for nocturnal polysomnography (NPSG). Initially, the patients will fill out a sinonasal and sleep questionnaire, have their medical history reviewed, undergo anterior nasal examination, and undergo acoustic rhinometry recordings before and after their NPSG. OSA patients will have these repeated at 1 month and 1 year after their initial NPSG.
Relevance/Analysis
These data will elucidate the effects of nCPAP on particular anatomic regions and components of the nose, the acute versus long-term effects of nCPAP on intranasal geometry, and the effects of different pressure levels of nCPAP on intranasal geometry. Appropriate medical and/or surgical intervention could be designed based on these results to increase patient compliance, reduce anatomic resistance to nCPAP, or to repair alterations in cartilaginous structures that may occur over time.
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Otolaryngology Surgery
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First published: 07/15/02 Last updated: 11/24/09
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