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Robert A. Haworth, PhD

Photograph of Robert A. Haworth, PhD

Distinguished Scientist, Division of Cardiothoracic Surgery

H4/331 Clinical Science Center
600 Highland Avenue
Madison,WI 53792-3236

Office: (608) 263-1339

FAX: (608) 265-9255

haworth@surgery.wisc.edu

Education

  • PhD, Biophysics, Manchester University, Manchester, England, 1972

Research Interests

Dr. Haworth has research interests in cardiac physiology, especially in relation to calcium homeostasis and energy metabolism. His research currently focuses in three areas: 1) the control of calcium fluxes in excitation-contraction coupling; 2) changes in excitation-contracton coupling associated with heart failure; and 3) new approaches to heart preservation for transplantation.

Active Grants

DyToCy Computer Model

"Ca transients from Ca channel activity in rat cardiac myocytes reveal the dynamics of dyad cleft and troponin C Ca binding" Sivan Vadakkadath Meethal, Katherine T. Potter, David Redon, Dennis M. Heisey, Robert A. Haworth (published in American Journal of Physiology-Cell Physiology 286(2): C302-316 (2004))

The instructions for downloading this model, the associated text file and model can be found here.

Recent Publications

  • Meethal SV, Potter KT, Redon D, Munoz-del-Rio A, Kamp TJ, Valdivia HH, Haworth RA. Structure-function relationships of Ca spark activity in normal and failing cardiac myocytes as revealed by flash photography., Cell Calcium. 2007 Feb;41(2):123-34.
    [PubMed ID: 16837043]
  • He JQ, Balijepalli RC, Haworth RA, Kamp TJ. Crosstalk of beta-adrenergic receptor subtypes through Gi blunts beta-adrenergic stimulation of L-type Ca2+ channels in canine heart failure., Circ. Res. 2005 Sep 16;97(6):566-73.
    [PubMed ID: 16100050]
  • Lokuta AJ, Maertz NA, Meethal SV, Potter KT, Kamp TJ, Valdivia HH, Haworth RA. Increased nitration of sarcoplasmic reticulum Ca2+-ATPase in human heart failure., Circulation. 2005 Mar 1;111(8):988-95.
    [PubMed ID: 15710754]
  • Valdivia CR, Chu WW, Pu J, Foell JD, Haworth RA, Wolff MR, Kamp TJ, Makielski JC. Increased late sodium current in myocytes from a canine heart failure model and from failing human heart., J. Mol. Cell. Cardiol. 2005 Mar;38(3):475-83.
    [PubMed ID: 15733907]
  • Knes JM, Hansen TN, Gilligan B, Woo H, Mangino M, Haworth RA, Southard JH. Loss of endothelium-dependent relaxation in abdominal aorta preserved in a co-storage system., Transpl. Int. 2005 Jan;17(11):699-706.
    [PubMed ID: 15551051]
  • All Publications

 

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Cardiothoracic Surgery - University of Wisconsin Department of Surgery
First published: 07/15/02 Last updated: 07/05/08 webmaster@surgery.wisc.edu
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