Pheochromocytoma
Most pheochromocytoma tumors grow on the adrenal glands, which are
situated at the top of the kidneys. Pheochromocytoma is a tumor made
up of adrenal gland cells that secretes excessive amounts of epinephrine
and norepinephrine, which regulate heart rate and blood pressure.
Deficiencies of iron or copper and diets high in manganese have been
associated with pheochromocytoma although the cause of the tumors is
not yet known. Risk factors associated with the condition include family
history of pheochromocytoma, tumors in other glands of the body or other
hormonal disorders.
Symptoms
Symptoms can be present many times a day, or as infrequently as once
every few months. They include:
- Severe headaches
- Excessive sweating
- Involuntary trembling
- Fast heart rate or pounding heart bea
- Tingling, burning, numbness in the legs and feet
- Chest pain and pain in the lower chest or upper abdomen
Diagnosis
Tests can include:
- 24-hour urine testing to measure amounts of certain hormones
produced by the adrenal glands
- Blood testing
- CAT scan, ultrasound, MRI and other imaging tests
Treatment
If surgery is necessary to remove a tumor, patients are placed on
medications to control their blood pressure for a treatment period
of four to six weeks prior to surgery. The majority of pheochromocytoma
tumors can be removed in a minimally-invasive surgical procedure called
laparoscopic adrenalectomy. Most patients are able to go home the
day after surgery.
If the tumor is cancerous, several treatment options are available,
including surgery, chemotherapy and radiation.
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