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M. Kunnimalaiyaan, Ph.D.
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Muthusamy Kunnimalaiyaan, PhD

Senior Scientist, Director,
Endocrine Surgery Research Lab,
Division of General Surgery

K4/643 Clinical Science Center
600 Highland Avenue
Madison, WI 53792-7375

Office: (608) 265-4111

 kunni@surgery.wisc.edu

Education

  • PhD, Indian Agricultural Research Institute, New Delhi, India, 1992

Research Interests

Dr. Kunnimalaiyaan has twelve years of postdoctoral experience in the fields of Biotechnology, microbiology, molecular biology, and Plant biology with eight years of research on DNA replication of both plant and bacteria. His current focus is on the Role of Notch-1 and Ras/raf-1 signaling pathways in Gastrointestinal Neuroendocrine tumors. He has worked on cancer biology/signaling pathways (Notch-1 and Ras/raf-1) since 2001.

Grants

  • Regulating neuroendocrine phenotype in cancer, National Institute of Health R01, Co-investigator, 2006-2011
  • Molecular targeting therapy for pancreatic cancer, University of Wisconsin Foundation, 2006
  • Role of lithium chloride in tumor suppression of neuroendocrine, Robert Draper Technology Innovation Award, 2005
  • Construction of Stable but Inducible Notch-1 and its Role in Medullary Thyroid Cancer, Medical School Research Committee, 2003-2004

Recent Publications

  • Adler JT, Hottinger DG, Kunnimalaiyaan M, Chen H. Inhibition of the PI3K pathway suppresses hormonal secretion and limits growth in pheochromocytoma cells., World journal of surgery. 2009 Nov;33(11):2452-7.
    [PubMed ID: 19669229]
  • Pitt SC, Chen H, Kunnimalaiyaan M. Inhibition of phosphatidylinositol 3-kinase/Akt signaling suppresses tumor cell proliferation and neuroendocrine marker expression in GI carcinoid tumors., Ann. Surg. Oncol. 2009 Oct;16(10):2936-42.
    [PubMed ID: 19588205]
  • Pitt SC, Chen H, Kunnimalaiyaan M. Phosphatidylinositol 3-kinase-Akt signaling in pulmonary carcinoid cells., J. Am. Coll. Surg. 2009 Jul;209(1):82-8.
    [PubMed ID: 19651067]
  • Chen JY, Cook MR, Pinchot SN, Kunnimalaiyaan M, Chen H. MG-132 Inhibits Carcinoid Growth and Alters the Neuroendocrine Phenotype., J. Surg. Res. 2009 Jun 21;():.
    [PubMed ID: 19765735]
  • Goodell CA, Belisle JA, Gubbels JA, Migneault M, Rancourt C, Connor J, Kunnimalaiyaan M, Kravitz R, Tucker W, Zwick M, Patankar MS. Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies., Journal of ovarian research. 2009;2(1):8.
    [PubMed ID: 19538730]
  • All Publications

Awards

Rising Star 1st place award for the best research presentation (Poster), North American Neuroendocrine Tumor Society and Carcinoid Cancer Foundation, Portland, OR, 2006

 

 

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General Surgery University of Wisconsin Department of Surgery
First published: 07/15/02 Last updated: 11/24/09 webmaster@surgery.wisc.edu
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