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Madison, Wisconsin – Babies born without nerves in their large intestines, a condition known as Hirschsprung’s disease, could benefit from two new studies in mice that shed light on how the condition develops.

Most new parents can recall hospital nurses checking the diaper for the baby’s first bowel movement. The reason is that one in 5,000 babies is born with Hirschsprung’s disease, which leads to severe constipation and intestinal obstruction.

Dr. Ankush Gosain treats babies with congentital digestive tract disorders at the CHARM (for children with Cloaca, Hirschsprung’s disease, and AnoRectal Malformations) clinic. He says that babies with Hirshsprung’s disease undergo surgery to remove the part of the intestine that lacks nerves, reattaching the healthy intestine to the anus.

His recent study findings were published in the journal Neurogastroenterology & Motility.

You can read the full news release as well as journal publications here. Copyright © 2016 The Board of Regents of the University of Wisconsin System