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Lian-Wang Guo, PhD

Contact Dr. Guo


(608) 262-6269

1111 Highland Avenue
Madison, WI 53705-2275

Lian-Wang Guo, PhD

Honorary Associate


  • PhD, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

Research Interests

Dr. Guo’s laboratory is interested in identifying novel causative processes in the development of restenosis, a common recurrent vascular disease. The long-term goal is to find better interventional avenues for effective amelioration of restenosis, through translational endeavors in close association with investigators across other disciplines such as biomedical engineering and drug screening.

Dr. Guo's Lab

  • Sigma-1 Chaperone-Mediated in vivo Neuroprotection in the Retina
    Funding Agency: National Institutes of Health
    Principal Investigator(s): Lian-Wang Guo, PhD
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Recent Publications
  • Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice.
    Li J, Zhao L, Urabe G, Fu Y, Guo LW
    Mol. Vis. 2017; 23():149-159.
    [PubMed ID: 28356707, PMC ID: 5360452]
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  • Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol.
    Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder BY, Urabe G, Shi Y, DiRenzo D, Goel SA, Zhou Y, Little C, Roenneburg DA, Shi XD, Li L, Murphy WL, Kent KC, Ke J, Guo LW
    Sci Rep 2017 Feb 06; 7():41916.
    [PubMed ID: 28165488, PMC ID: 5292946]
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  • Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration.
    Zhao L, Li J, Fu Y, Zhang M, Wang B, Ouellette J, Shahi PK, Pattnaik BR, Watters JJ, Wong WT, Guo LW
    J Neuroinflammation 2017 Jan 19; 14(1):14.
    [PubMed ID: 28103888, PMC ID: 5248448]
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  • An intraocular drug delivery system using targeted nanocarriers attenuates retinal ganglion cell degeneration.
    Zhao L, Chen G, Li J, Fu Y, Mavlyutov TA, Yao A, Nickells RW, Gong S, Guo LW
    J Control Release 2017 Feb 10; 247():153-166.
    [PubMed ID: 28063892, PMC ID: 5323250]
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  • Peeking into Sigma-1 Receptor Functions Through the Retina.
    Mavlyutov TA, Guo LW
    Adv. Exp. Med. Biol. 2017; 964():285-297.
    [PubMed ID: 28315278]
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