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Lian-Wang Guo, PhD

Contact Dr. Guo


(608) 262-6269

MADISON, WI 53705-2275

Lian-Wang Guo, PhD

Assistant Professor


  • PhD, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences

Research Interests

Dr. Guo’s laboratory is interested in identifying novel causative processes in the development of restenosis, a common recurrent vascular disease. The long-term goal is to find better interventional avenues for effective amelioration of restenosis, through translational endeavor in close association with Dr. Craig Kent’s lab and investigators across other disciplines such as biomedical engineering and drug screening.

Dr. Guo's Lab

  • Sigma-1 Chaperone-Mediated in vivo Neuroprotection in the Retina
    Funding Agency: National Institutes of Health
    Principal Investigator(s): Lian-Wang Guo, PhD
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Recent Publications
  • Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia.
    Shi X, Guo LW, Seedial S, Takayama T, Wang B, Zhang M, Franco SR, Si Y, Chaudhary MA, Liu B, Kent KC
    Stem Cells 2016 Jun 24.
    [PubMed ID: 27340942]
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  • Periadventitial drug delivery for the prevention of intimal hyperplasia following open surgery.
    Chaudhary MA, Guo LW, Shi X, Chen G, Gong S, Liu B, Kent KC
    J Control Release 2016 Jul 10; 233():174-80.
    [PubMed ID: 27179635, PMC ID: 4912910]
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  • A crosstalk between TGF-β/Smad3 and Wnt/β-catenin pathways promotes vascular smooth muscle cell proliferation.
    DiRenzo DM, Chaudhary MA, Shi X, Franco SR, Zent J, Wang K, Guo LW, Kent KC
    Cell. Signal. 2016 May; 28(5):498-505.
    [PubMed ID: 26912210, PMC ID: 4788971]
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  • Development of sigma-1 (σ1) receptor fluorescent ligands as versatile tools to study σ1 receptors.
    Abate C, Riganti C, Pati ML, Ghigo D, Berardi F, Mavlyutov T, Guo LW, Ruoho A
    Eur J Med Chem 2016 Jan 27; 108():577-85.
    [PubMed ID: 26717207, PMC ID: 4755300]
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  • The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes.
    Chu UB, Mavlyutov TA, Chu ML, Yang H, Schulman A, Mesangeau C, McCurdy CR, Guo LW, Ruoho AE
    EBioMedicine 2015 Nov; 2(11):1806-13.
    [PubMed ID: 26870805, PMC ID: 4740303]
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