Education

• PhD, Indian Agricultural Research Institute, New Delhi, India, 1992

Research Interests

Dr. Kunnimalaiyaan has twelve years of postdoctoral experience in the fields of biotechnology, microbiology, molecular biology, and plant biology with eight years of research on DNA replication of both plant and bacteria. His current focus is on the Role of Notch-1 and Ras/raf-1 signaling pathways in Gastrointestinal Neuroendocrine tumors. He has worked on cancer biology/signaling pathways (Notch-1 and Ras/raf-1) since 2001.

Dr. Chen's Lab

Recent Publications

• Antiproliferative effect of chrysin on anaplastic thyroid cancer.
  Phan T, Yu XM, Kunnimalaiyaan M, Chen H
  J. Surg. Res. 2011 Sep; 170(1):84-8.
  [PubMed ID: 21571321, PMC ID: 3154442]
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• Expression of the active Notch1 decreases MTC tumor growth in vivo.
  Jaskula-Sztul R, Pisarnturakit P, Landowski M, Chen H, Kunnimalaiyaan M
  J. Surg. Res. 2011 Nov; 171(1):23-7.
  [PubMed ID: 21571316, PMC ID: 3157562]
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• A preclinical and clinical study of lithium in low-grade neuroendocrine tumors.
  Lubner SJ, Kunnimalaiyaan M, Holen KD, Ning L, Ndiaye M, Loconte NK, Mulkerin DL, Schelman WR, Chen H
  Oncologist 2011; 16(4):452-7.
  [PubMed ID: 21393344, PMC ID: 3119207]
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• Hesperetin, a potential therapy for carcinoid cancer.
  Zarebczan B, Pinchot SN, Kunnimalaiyaan M, Chen H
  Am. J. Surg. 2011 Mar; 201(3):329-32; discussion 333.
  [PubMed ID: 21367373, PMC ID: 3073682]
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• Resveratrol induces Notch2-mediated apoptosis and suppression of neuroendocrine markers in medullary thyroid cancer.
  Truong M, Cook MR, Pinchot SN, Kunnimalaiyaan M, Chen H
  Ann. Surg. Oncol. 2011 May; 18(5):1506-11.
  [PubMed ID: 21184191, PMC ID: 3078954]
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