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Toshio Takayama, MD, PhD

Contact Dr. Takayama


(608) 265-4420

600 Highland Avenue
Madison, WI 53792

Toshio Takayama, MD, PhD

Clinical Assistant Professor


  • MD, Faculty of Medicine, University of Tokyo, 2000
  • PhD, Graduate School of Medicine, University of Tokyo, 2009

Department of Cardiovascular Surgery
Morinomiya Hospital
Osaka, Japan

Research Interests

Dr. Kent's Lab

Dr. Yamanouchi's Lab

Recent Publications
  • Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol.
    Zhu Y, Takayama T, Wang B, Kent A, Zhang M, Binder BY, Urabe G, Shi Y, DiRenzo D, Goel SA, Zhou Y, Little C, Roenneburg DA, Shi XD, Li L, Murphy WL, Kent KC, Ke J, Guo LW
    Sci Rep 2017 Feb 06; 7():41916.
    [PubMed ID: 28165488, PMC ID: 5292946]
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  • Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia.
    Shi X, Guo LW, Seedial S, Takayama T, Wang B, Zhang M, Franco SR, Si Y, Chaudhary MA, Liu B, Kent KC
    Stem Cells 2016 Jun 24.
    [PubMed ID: 27340942, PMC ID: 5113668]
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  • BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries.
    Wang B, Zhang M, Takayama T, Shi X, Roenneburg DA, Kent KC, Guo LW
    EBioMedicine 2015 Nov; 2(11):1650-61.
    [PubMed ID: 26870791, PMC ID: 4740308]
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  • Aortic Arch Morphology and Aortic Length in Patients with Dissection, Traumatic, and Aneurysmal Disease.
    Alberta HB, Takayama T, Smits TC, Wendorff BB, Cambria RP, Farber MA, Jordan WD, Patel V, Azizzadeh A, Rovin JD, Matsumura JS
    Eur J Vasc Endovasc Surg 2015 Dec; 50(6):754-60.
    [PubMed ID: 26371414]
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  • Halofuginone stimulates adaptive remodeling and preserves re-endothelialization in balloon-injured rat carotid arteries.
    Guo LW, Wang B, Goel SA, Little C, Takayama T, Shi XD, Roenneburg D, DiRenzo D, Kent KC
    Circ Cardiovasc Interv 2014 Aug; 7(4):594-601.
    [PubMed ID: 25074254, PMC ID: 4140988]
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  • TGF-β/Smad3 inhibit vascular smooth muscle cell apoptosis through an autocrine signaling mechanism involving VEGF-A.
    Shi X, Guo LW, Seedial SM, Si Y, Wang B, Takayama T, Suwanabol PA, Ghosh S, DiRenzo D, Liu B, Kent KC
    Cell Death Dis 2014 Jul 10; 5():e1317.
    [PubMed ID: 25010983, PMC ID: 4123076]
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  • A rapamycin-releasing perivascular polymeric sheath produces highly effective inhibition of intimal hyperplasia.
    Yu X, Takayama T, Goel SA, Shi X, Zhou Y, Kent KC, Murphy WL, Guo LW
    J Control Release 2014 Oct 10; 191():47-53.
    [PubMed ID: 24852098, PMC ID: 4156896]
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  • Aneurysmal disease: the abdominal aorta.
    Takayama T, Yamanouchi D
    Surg. Clin. North Am. 2013 Aug; 93(4):877-91, viii.
    [PubMed ID: 23885935]
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  • True abdominal aortic aneurysm in Marfan syndrome.
    Takayama T, Miyata T, Nagawa H
    J. Vasc. Surg. 2009 May; 49(5):1162-5.
    [PubMed ID: 19307079]
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  • The growth of a vascular network inside a collagen-citric acid derivative hydrogel in rats.
    Takayama T, Taguchi T, Koyama H, Sakari M, Kamimura W, Takato T, Miyata T, Nagawa H
    Biomaterials 2009 Jul; 30(21):3580-7.
    [PubMed ID: 19362365]
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