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Active Clinical Trials

Cardiothoracic Surgery Clinical Trials

Rate Control Versus Rhythm Control For Postoperative Atrial Fibrillation
Principal Investigator(s): Shahab Akhter, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT02132767]
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Safety & Efficacy of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in LVAD Recipients
Principal Investigator(s):
Shahab Akhter, MD
Status: Recruiting
[ClinicalTrials.gov: NCT02362646]
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Interagency Registry for Mechanically Assisted Circulatory Support (Intermacs)
Principal Investigator(s): Takushi Kohmoto, MD, PhD
Status: Recruiting
[ClinicalTrials.gov: NCT00119834]
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General Surgery Clinical Trials

Acute Lung Injury Ventilator Evaluation (ALIVE) Trial: Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation in Trauma Patients
Principal Investigator(s):
Suresh K. Agarwal, Jr., MD, FACS, FCCM, FCCP
Status: Recruiting
[ClinicalTrials.gov: NCT01901354]
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Thoratec Corporation MOMENTUM 3, Multi-center Study of MagLev Technology in Patients Undergoing MCS Therapy With HeartMate 3™ IDE Clinical Study Protocol
Principal Investigator(s): Shahab Akhter, MD
Status: Recruiting
[ClinicalTrials.gov: NCT02224755]
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A Phase II Study Evaluating the Role of Sentinel Lymph Node Surgery and Axillary Lymph Node Dissection Following Preoperative Chemotherapy in Women With Node Positive Breast Cancer (T1-4, N1-2, M0) at Initial Diagnosis
Principal Investigator(s):
Catherine W Beckman, MD, Heather B Neuman, MD, MS, FACS, Lee G Wilke, MD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00881361]
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A Phase III Study of Chemotherapy and Chemoradiotherapy With or Without Algenpantucel-L (HyperAcute®-Pancreas) Immunotherapy in Subjects With Surgically Resected Pancreatic Cancer
Principal Investigator(s): Clifford S Cho, MD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01072981]
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A Phase III Study of Chemotherapy With or Without Algenpantucel-L (HyperAcute®-Pancreas) Immunotherapy in Subjects With Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer
Principal Investigator(s): Clifford S Cho, MD, FACS
Status: Recruiting
[ClinicalTrials.gov: NCT01836432]
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A Prospective, Single-blind, Randomized, Phase III Study to Evaluate the Safety and Efficacy of Fibrin Sealant Grifols (FS Grifols) as an Adjunct to Hemostasis During Parenchymous Tissue Open Surgeries
Principal Investigator(s): Clifford S Cho, MD, FACS, Emily R. Winslow, MD, FACS
Status: Recruiting
[ClinicalTrials.gov: NCT01754480]
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Strata2014
Principal Investigator(s): Lee D Faucher, MD
Status: New
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A Prospective, Multi-Center Study of Phasix™ Mesh for Ventral or Incisional Hernia Repair.
Principal Investigator(s): Jacob A. Greenberg, MD, EdM
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01961687]
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A Prospective Post-Market Clinical Evaluation of Miromatrix Biological Mesh for Ventral Hernia Repair
Principal Investigator(s): Jacob A. Greenberg, MD, EdM
Status: Recruiting
[ClinicalTrials.gov: NCT02408458]
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A Phase III Prospective Randomized Trial Comparing Laparoscopic-Assisted Resection Versus Open Resection for Rectal Cancer
Principal Investigator(s): Gregory D Kennedy, MD, PhD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00726622]
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Pre-operative Tamsulosin for the Prevention of Post-operative Urinary Retention: a Randomized, Double-blind, Placebo-controlled Trial
Principal Investigator(s):
Gregory D Kennedy, MD, PhD
Status: Recruiting
[ClinicalTrials.gov: NCT02486653]
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A Phase III Multicenter Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection Versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patients With Molecular or Histopathological Evidence of Metastases in the Sentinel Node
Principal Investigator(s): Heather B Neuman, MD, MS, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00389571]
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A Phase III Multicenter Randomized Trial of Sentinel Lymphadenectomy and Complete Lymph Node Dissection Versus Sentinel Lymphadenectomy Alone in Cutaneous Melanoma Patients With Molecular or Histopathological Evidence of Metastases in the Sentinel Node
Principal Investigator(s): Heather B Neuman, MD, MS, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00297895]
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MILND in Patients with Melanoma
Principal Investigator(s): Heather B Neuman, MD, MS, FACS
Status: New
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A Prospective, Multi-center Registry for Patients With Short Bowel Syndrome
Principal Investigator(s): Peter F Nichol, MD, PhD
Status: Recruiting
[ClinicalTrials.gov: NCT01990040]
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TED-C14-006/ 2-dose Teduglutide
Principal Investigator(s): Peter F Nichol, MD, PhD
Status: New
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Changes in 13CO2/12CO2 Delta Value in Exhaled Breath as an Early Indicator of Infection in Adult Trauma Subjects
Principal Investigator(s): Ann P O’Rourke, MD, MPH
Status: Recruiting
[ClinicalTrials.gov: NCT02258022]
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Central Neck Dissection in Patients With Clinical Node Negative Thyroid Cancer
Principal Investigator(s): Rebecca S Sippel, MD
Status: Recruiting
[ClinicalTrials.gov: NCT02138214]
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A Phase II Study of Preoperative Gemcitabine and Erlotinib Plus Pancreatectomy and Postoperative Gemcitabine and Erlotinib for Patients With Operable Pancreatic Adenocarcinoma
Principal Investigator(s):
Sharon M Weber, MD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00733746]
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A Phase II Study Evaluating the Efficacy and Safety of Ultratrace Iobenguane I 131 in Patients With Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma
Status: Recruiting
[ClinicalTrials.gov: NCT00874614]
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C. Diff
Status: New
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PRT-201-310
Status: New
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OTOLARYNGOLOGY Clinical Trials

Pharyngeal Pressures Manometry Study
Principal Investigator(s):
Timothy M McCulloch, MD
Status: Open To Accrual
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PARADIGHM
Principal Investigator(s): Rebecca S Sippel, MD
Status: New
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Thibeault R01
Principal Investigator(s): Susan Thibeault, PhD, CCC-SLP
Status: Closed To Accrual
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Post-extubation dysphagia
Status: New
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Swallowing Outcomes after Unilateral Injection Medialization in Patients with Vocal Fold Paralysis/P
Status: Irb Initial Approval
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The Effect on Time After Extubation on Aspiration Risk
Status: Recruiting
[ClinicalTrials.gov: NCT01849679]
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TRANSPLANT SURGERY Clinical Trials

Col(V) response in heart and lung transplantation
Principal Investigator(s): William J Burlingham, PhD
Status: Open To Accrual
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Identification and Mechanistic Investigations of Tolerant Transplant Recipients
Principal Investigator(s): William J Burlingham, PhD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01338779]
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Maternal Microchimerism and Neonatal Tolerance
Principal Investigator(s): William J Burlingham, PhD
Status: Open To Accrual
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Transplant Tolerance
Principal Investigator(s): William J Burlingham, PhD
Status: Open To Accrual
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A 24-month, Multi-center, Single Arm, Prospective Study to Evaluate Renal Function, Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.
Principal Investigator(s): Anthony M D’Alessandro, MD
Status: Recruiting
[ClinicalTrials.gov: NCT01598987]
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A Phase 2a, Randomized, Open-label, Active Control, Multi-Center Study to Assess the Efficacy and Safety of ASKP1240 in de Novo Kidney Transplant Recipients
Principal Investigator(s): Dixon Kaufman, MD, PhD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01780844]
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Islet Transplantation in Type 1 Diabetic Kidney Allograft Recipients: Efficacy of Islet After Kidney Transplantation (CIT-06)
Principal Investigator(s): Dixon Kaufman, MD, PhD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00468117]
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Randomized, Open Label, Multicenter Study of Belatacept-based Early Steroid Withdrawal Regimen With Alemtuzumab or rATG Induction Compared to Tacrolimus-based Early Steroid Withdrawal Regimen With rATG Induction in Renal Transplantation
Principal Investigator(s): Dixon Kaufman, MD, PhD, FACS
Status: Recruiting
[ClinicalTrials.gov: NCT01729494]
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Prognosis and Diagnosis of Fibroproliferative Disorders
Principal Investigator(s): Hans W. Sollinger, MD, PhD, FACS
Status: Open To Accrual
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Transplantation Clinical Trials

Mycophenolic Acid Monotherapy in Recipients of HLA-identical Living-Related Transplantation
Principal Investigator(s): William J Burlingham, PhD, Hans W. Sollinger, MD, PhD, FACS
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01053221]
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Islet Transplantation in Type 1 Diabetic Patients Using a Steroid-free Immunosuppression Protocol and Thiazolidinedione Insulin Sensitizers
Principal Investigator(s):
Jon S Odorico, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00214253]
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Vascular Surgery Clinical Trials

An Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for the Primary Treatment of Aneurysm of the Descending Thoracic Aortic
Principal Investigator(s): Charles W Acher, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00874250]
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Evaluation of the GORE® EXCLUDER® Iliac Branch Endoprosthesis for the Treatment of Common Iliac Artery Aneurysms or Aorto-iliac Aneurysms
Principal Investigator(s): Charles W Acher, MD
Status: Recruiting
[ClinicalTrials.gov: NCT01883999]
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A Phase 2, Randomized, Open-label (With Blinded Plasminogen Activator and Placebo Control Groups) Study to Evaluate the Effects of Different Intra-thrombus Infusion Regimens of Plasmin (Human) Compared to Plasminogen Activator and Placebo In Patients With Acute Lower Extremity Native Artery or Bypass Graft Occlusion
Principal Investigator(s): John R Hoch, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01222117]
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Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition With Evacetrapib in Patients at a High-Risk for Vascular Outcomes
Principal Investigator(s): John R Hoch, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01687998]
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GREAT’ Global Registry for Endovascular Aortic Treatment – Outcomes Evaluation
Principal Investigator(s): John R Hoch, MD
Status: Recruiting
[ClinicalTrials.gov: NCT01658787]
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INTREPID
Principal Investigator(s): John R Hoch, MD
Status: New
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Principal Investigator(s): John R Hoch, MD
Status: Open To Accrual
[ClinicalTrials.gov: NCT02060310]
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Carotid Revascularization With ev3 Arterial Technology Evolution Post Approval Study
Principal Investigator(s): Girma Tefera, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00530504]
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Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for Treatment of Acute Complicated Type B Aortic Dissection
Principal Investigator(s): Girma Tefera, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00908388]
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Evaluation of the GORE Conformable TAG® Thoracic Endoprosthesis for Treatment of Traumatic Transection of the Descending Thoracic Aorta
Principal Investigator(s): Girma Tefera, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00917852]
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Evaluation of the Long-term Safety and Performance of the Zenith® Fenestrated AAA Endovascular Graft Post-Approval Study
Principal Investigator(s): Girma Tefera, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01990950]
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Prospective Aneurysm Trial: High Angle Aorfix™ Bifurcated Stent Graft
Principal Investigator(s): Girma Tefera, MD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT00522535]
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Zenith® p-Branch® Pivotal Study
Principal Investigator(s): Girma Tefera, MD
Status: Not yet recruiting
[ClinicalTrials.gov: NCT02396199]
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A Multicenter, Open Label, Prospective, Non-randomized Study of the InCraft® Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSPIRATION)
Principal Investigator(s): Dai Yamanouchi, MD, PhD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01664078]
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A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study To Evaluate The Efficacy, Safety, And Tolerability Of Ixmyelocel-T In Subjects With Critical Limb Ischemia And No Options For Revascularization
Principal Investigator(s): Dai Yamanouchi, MD, PhD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01483898]
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Multicenter, Post-Market Study to Assess Outcomes of Patients Treated With the AFX System Compared to Other EVAR Devices for Endovascular Abdominal Aortic Aneurysm Repair: LEOPARD
Principal Investigator(s): Dai Yamanouchi, MD, PhD
Status: Recruiting
[ClinicalTrials.gov: NCT02407457]
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Pivotal Study of the Safety and Effectiveness of Autologous Bone Marrow Aspirate Concentrate (BMAC) for the Treatment of Critical Limb Ischemia Due to Peripheral Arterial Disease
Principal Investigator(s): Dai Yamanouchi, MD, PhD
Status: Active, not recruiting
[ClinicalTrials.gov: NCT01245335]
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