Genomics of Chronic Renal Allograft Rejection (The GoCAR Study)

Doctors have had success preventing certain types of kidney transplant rejection by
suppressing the immune system. However, an individual’s genetic make-up and the strength of
an immune response to a transplant may also determine whether a transplanted organ is
rejected. The purpose of this study is to look at the genetic profile and immune response of
people who have had kidney transplants and to correlate the findings with kidney transplant
rejection episodes. Donor genetic profiles will also be studied and correlated with the
recipient’s information.