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Authors Worley MJ, Aelion A, Caputo TA, Kent KC, Salemi A, Krieger KH, Goldstein MJ, Kuo DY, Slomovitz BM
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Journal Am. J. Obstet. Gynecol. Volume: 201 Issue: 6 Pages: 574.e1-5
Publish Date 2009 Dec
PubMed ID 19729144
PMC ID 4309800
Abstract

The aim of this study was to outline the surgical management and outcomes for patients diagnosed with intravenous leiomyomatosis with intracardiac extension at a single institution.This was a retrospective review of patients diagnosed with intravenous leiomyomatosis with intracardiac extension between 2002-2008.Four patients were identified. The surgical approach in 3 (75%) patients was a single-stage operation. Four (100%) patients presented with cardiac symptoms: 3 (75%) with syncope and 1 (25%) with an abnormal electrocardiogram. Mean age at presentation was 48 years (range, 42-58 years). Complete resection of tumor was obtained in 1 (25%) patient and 3 (75%) patients experienced incomplete resection. Mean follow-up, including surveillance imaging, was 25.5 months (range, 8-57 months) and all 4 patients (100%) are currently free of recurrence.Surgical excision remains an effective therapy for treating patients with benign metastasizing leiomyomatosis. Incomplete surgical resection may result in favorable response.

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