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Authors Pierre JF, Heneghan AF, Lawson CM, Wischmeyer PE, Kozar RA, Kudsk KA
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Journal JPEN J Parenter Enteral Nutr Volume: 37 Issue: 5 Suppl Pages: 51S-65S
Publish Date 2013 Sep
PubMed ID 24009249

The search to improve outcomes in critically ill patients through nutrition support has steadily progressed over the past 4 decades. One current approach to this problem is the addition of specific nutrients as primary therapy to improve host defenses and improve the outcome of critically ill patients. The field is referred to as “pharmaconutrition,” with the hope of focusing investigations on each nutrient to understand its pharmacological effects on immune and clinical outcomes. The purpose of this review is to describe some of the known physiological mechanisms of pharmaconutrients such as glutamine, arginine, ω-3 fatty acids, and selenium. Copyright © 2016 The Board of Regents of the University of Wisconsin System