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Authors Panwar A, Lindau R, Wieland A
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Journal Expert Rev Anticancer Ther
Publish Date 2014 Jan 8
PubMed ID 24397698

Premalignant lesions of the oral cavity present as visibly abnormal areas of mucosa and may be a source of significant anxiety for the patient and the clinician. Suspicious lesions should be biopsied to evaluate for dysplasia. The risk of malignant transformation may relate to patient characteristics, environmental risk factors and genetic alterations. Management of such lesions hinges on risk modification, surveillance, symptom management and directed biopsies. Excision or ablation of dysplastic lesions is indicated. We review the current evidence relating to management of premalignant lesions of the oral mucosa and make recommendations for practice patterns. Copyright © 2016 The Board of Regents of the University of Wisconsin System