Tausif Alam, PhD

Associate Scientist, Division of Transplantation H4/725 Clinical Science Center 600 Highland Avenue Madison, WI 53792-7375 Office: (608) 265-5498 FAX: (608) 263-7652  alam@surgery.wisc.edu

Education

• PhD, Aligarh Muslim University, Aligarh, India, 1978

Research Interests

Dr. Alam's current research focuses on developing a novel insulin gene therapy based treatment of insulin dependant diabetes mellitus (Type I) that relies on the use of autologous cells transduced to produce insulin in a glucose-dependent manner.

Active Grants

• Hepatocyte Based Novel Insulin Gene Therapy

Recent Publications

• Torrealba JR, Colburn M, Golner S, Chang Z, Scheunemann T, Fechner JH, Roenneburg D, Hu H, Alam T, Kim HT, Kanmaz T, Oberley T, Knechtle SJ, Hamawy MM. Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy., Am. J. Transplant. 2005 Jan;5(1):58-67.
  [PubMed ID: 15636612]
• Nett PC, Sollinger HW, Alam T. Hepatic insulin gene therapy in insulin-dependent diabetes mellitus., Am. J. Transplant. 2003 Oct;3(10):1197-203.
  [PubMed ID: 14510692]
• Alam T, Sollinger HW. Glucose-regulated insulin production in hepatocytes., Transplantation. 2002 Dec 27;74(12):1781-7.
  [PubMed ID: 12499898]
• Peters D, Tsuchida M, Manthei ER, Alam T, Cho CS, Knechtle SJ, Hamawy MM. Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506., Blood. 2000 May 1;95(9):2733-41.
  [PubMed ID: 10779414]
• Tsuchida M, Manthei ER, Alam T, Knechtle SJ, Hamawy MM. Regulation of T cell receptor- and CD28-induced tyrosine phosphorylation of the focal adhesion tyrosine kinases Pyk2 and Fak by protein kinase C. A role for protein tyrosine phosphatases., J. Biol. Chem. 2000 Jan 14;275(2):1344-50.
  [PubMed ID: 10625683]
• All Publications

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Transplantation - University of Wisconsin Department of Surgery
First published: 07/15/02 Last updated: 08/19/08 webmaster@surgery.wisc.edu
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