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Publications & Funding

1. McIntosh BE, Brown ME, Duffin BM, Maufort JP, Vereide DT, Slukvin II, Thomson JA. Nonirradiated NOD,B6.SCID Il2rγ-/- Kit(W41/W41) (NBSGW) mice support multilineage engraftment of human hematopoietic cells. Stem Cell Reports 2015 Feb 10; 4(2):171-80.
[PubMed ID: 25601207, PMCID: 4325197]
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2. Lockridge JL, Zhou Y, Becker YA, Ma S, Kenney SC, Hematti P, Capitini CM, Burlingham WJ, Gendron-Fitzpatrick A, Gumperz JE. Mice engrafted with human fetal thymic tissue and hematopoietic stem cells develop pathology resembling chronic graft-versus-host disease. Biol. Blood Marrow Transplant. 2013 Sep; 19(9):1310-22.
[PubMed ID: 23806772, PMCID: 3755109]
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3. Ma SD, Yu X, Mertz JE, Gumperz JE, Reinheim E, Zhou Y, Tang W, Burlingham WJ, Gulley ML, Kenney SC.
An Epstein-Barr Virus (EBV) mutant with enhanced BZLF1 expression causes lymphomas with abortive lytic EBV infection in a humanized mouse model.
J. Virol.
2012 Aug; 86(15):7976-87.

[PubMed ID: 22623780, PMCID: 3421695]

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4. Kalscheuer H, Danzl N, Onoe T, Faust T, Winchester R, Goland R, Greenberg E, Spitzer TR, Savage DG, Tahara H, Choi G, Yang YG, Sykes M. A model for personalized in vivo analysis of human immune responsiveness. Sci Transl Med 2012 Mar 14; 4(125):125ra30.
[PubMed ID: 22422991, PMCID: 3697150]
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5. Lockridge JL, Chen X, Zhou Y, Rajesh D, Roenneburg DA, Hegde S, Gerdts S, Cheng TY, Anderson RJ, Painter GF, Moody DB, Burlingham WJ, Gumperz JE.
Analysis of the CD1 antigen presenting system in humanized SCID mice.
2011; 6(6):e21701.

[PubMed ID: 21738769, PMCID: 3128084]

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6. Ma SD, Hegde S, Young KH, Sullivan R, Rajesh D, Zhou Y, Jankowska-Gan E, Burlingham WJ, Sun X, Gulley ML, Tang W, Gumperz JE, Kenney SC.
A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas.
J. Virol.
2011 Jan; 85(1):165-77.

[PubMed ID: 20980506, PMCID: 3014199]

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7. Rajesh D, Zhou Y, Jankowska-Gan E, Roenneburg DA, Dart ML, Torrealba J, Burlingham WJ. Th1 and Th17 immunocompetence in humanized NOD/SCID/IL2rgammanull mice. Hum. Immunol. 2010 Jun; 71(6):551-9.
[PubMed ID: 20298731, PMCID: 2875879]
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8. Lan P, Tonomura N, Shimizu A, Wang S, Yang YG. Reconstitution of a functional human immune system in immunodeficient mice through combined human fetal thymus/liver and CD34+ cell transplantation. Blood 2006 Jul 15; 108(2):487-92.
[PubMed ID: 16410443]
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The Humanized Mouse Core is funded by fees for service. Additionally, the Core is generously supported by the University of Wisconsin Department of Surgery, the School of Medicine and Public Health, the UW Stem Cell and Regenerative Medicine Center, and a grant from the UW Institute for Clinical and Translational Research under NIH awards UL1TR000427 and TL1TR000429. Matthew Brown receives funding from the UW-Madison Cellular and Molecular Pathology Graduate Program under NIH grant number T32 GM081061.

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