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Gregory D Kennedy, MD, PhD

Contact Dr. Kennedy


(608) 263-2521

MADISON, WI 53792-3284

Gregory D Kennedy, MD, PhD

Associate Professor
Vice Chairman of Quality, Department of Surgery
Chief, Section of Colorectal Surgery
Division of General Surgery


  • MD, University of Washington School of Medicine, Seattle, WA, 1996
  • PhD, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2003
  • General Surgery Residency, University of Wisconsin School of Medicine and Public Health, Madison, WI, 1996-1998, 2003-2006
  • Colon and Rectal Surgery Fellowship, Mayo Clinic, Rochester, MN, 2006-2007

Clinical Specialties

Dr. Kennedy is certified by the American Board of Colon and Rectal Surgery and by the American Board of Surgery. In addition, he is a Fellow of the American College of Surgeons (FACS) and a Fellow of the American Society of Colon and Rectal Surgery (FASCRS). Dr. Kennedy’s main interest is in laparoscopic approaches to complex colorectal disease. He has experience with all advanced laparoscopic and minimally invasive approaches including single incision laparoscopy and robotic surgery. His clinical areas of expertise include: colon cancer, rectal cancer, inflammatory bowel disease, benign conditions of colon, rectum, and anus, and endoscopic treatment of colonic disease.

Operations that are laparoscopically performed include: sphincter preserving surgery for rectal cancer, abdominoperineal resection for rectal cancer, total and partial colon resection, restorative proctocolectomy for ulcerative colitis or prophylactically for familial cancer syndromes. Dr. Kennedy also provides the spectrum of colon and rectal surgical procedures including abscess drainage, fistulotomy, and hemorrhoidectomy.

Research Interests

Dr. Kennedy’s funded laboratory effort is focused on chemoprevention of colon and rectal cancer. His laboratory uses genetic models to better understand how chemicals prevent tumor formation and what genetic pathways are responsible for their effects. The ultimate goal of this effort is to identify targeted agents that are better tolerated by patients in hopes of preventing colon and rectal cancer.

In addition to a basic laboratory research program, Dr. Kennedy is interested in quality improvement research. His research focuses on gaining a better understanding of postoperative complications. Our hope is that by understanding the types of complications and their timing we can start to better anticipate complications and ultimately prevent them. Our prevention work uses systems approaches to improve the quality of our patient care. Through these approaches we have dropped our rate of wound complications and seen our length of stay shortened.

UW Colon and Rectal Surgery Lab

Active Clinical Trials

Recent Publications
  • Does Anastomotic Leak Contribute to High Failure-to-rescue Rates?
    Tevis SE, Carchman EH, Foley EF, Heise CP, Harms BA, Kennedy GD
    Ann. Surg. 2015 Nov 18.
    [PubMed ID: 26587851]
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  • Process improvement in surgery.
    Minami CA, Sheils CR, Bilimoria KY, Johnson JK, Berger ER, Berian JR, Englesbe MJ, Guillamondegui OD, Hines LH, Cofer JB, Flum DR, Thirlby RC, Kazaure HS, Wren SM, O'Leary KJ, Thurk JL, Kennedy GD, Tevis SE, Yang AD
    Curr Probl Surg 2016 Feb; 53(2):62-96.
    [PubMed ID: 26806271]
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  • Variation Reduction to Reduce Readmission: A Figment of Imagination or Reality of the Future?
    Weber SM, Kennedy GD
    JAMA Surg 2015 Nov 1; 150(11):1049-50.
    [PubMed ID: 26244632]
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  • Aryl hydrocarbon receptor-dependent apoptotic cell death induced by the flavonoid chrysin in human colorectal cancer cells.
    Ronnekleiv-Kelly SM, Nukaya M, Díaz-Díaz CJ, Megna BW, Carney PR, Geiger PG, Kennedy GD
    Cancer Lett. 2016 Jan 1; 370(1):91-9.
    [PubMed ID: 26515162, PMC ID: 4698318]
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  • Some Important Deficiencies in the Development, Validation, and Reporting of a Prediction Model-Reply.
    Tevis SE, Kennedy GD
    JAMA Surg 2015 Sep; 150(9):915-6.
    [PubMed ID: 26200594]
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