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Authors Moyer TJ, Kassam HA, Bahnson ES, Morgan CE, Tantakitti F, Chew TL, Kibbe MR, Stupp SI
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Journal Small Volume: 11 Issue: 23 Pages: 2750-5
Publish Date 2015 Jun
PubMed ID 25649528
PMC ID 4478239

Targeting of vascular intervention by systemically delivered supramolecular nanofibers after balloon angioplasty is described. Tracking of self-assembling peptide amphiphiles using fluorescence shows selective binding to the site of vascular intervention. Cylindrical nanostructures are observed to target the site of arterial injury, while spherical nanostructures with an equivalent diameter display no binding.

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