Department of Surgery
University of Wisconsin School of Medicine and Public Health

Bo Liu, PhD

Professor

  • Division of Vascular Surgery

liub@surgery.wisc.edu
(608) 263-5931

Wisconsin Institutes for Medical Research (WIMR) BLDG. 1485
1111 Highland Avenue
Madison, WI 53705-2275

Education

  • MS, Biology, Beijing University, Beijing, China, 1986
  • PhD, Biochemistry, SUNY Downstate, New York, NY, 1993
  • Postdoctoral fellow, Signal transduction; protein degradation, Columbia University, New York, NY, 1994-1996
  • Postdoctoral fellow, Transcription regulation; signal transduction, Memorial Sloan-Kettering Cancer Center, New York, NY, 1996-1999

Research Interests

The primary focus of Dr. Liu’s research is the biology of blood vessels. Specifically, Dr. Liu and her trainees study the cellular and molecular pathologies of restenosis and abdominal aortic aneurysm, two common vascular disorders that are in critical need of effective pharmacological treatments. Their experimental approach combines in vitro molecular and biochemical methodologies with transgenic, gene knockout, adenoviral and surgical technologies. Current research topics include cell apoptosis, programmed necrosis, vascular inflammation, progenitor cell recruitment, as well as matrix biology. Additional research interests are gene therapy and nanotechnology. To effectively study human disease, Dr. Liu has established productive collaborations with basic scientists and clinicians from a wide range of scientific and medical disciplines. Dr. Liu is also a devoted mentor, whose lab environment fosters creative thinking, multidisciplinary approaches, independence, and collaboration.

Dr. Bo Liu’s Lab

Recent Publications

  • A vein wall cell atlas of murine venous thrombosis determined by single-cell RNA sequencing.
    DeRoo E, Zhou T, Yang H, Stranz A, Henke P, Liu B
    Commun Biol 2023 Jan 31; 6(1): 130
    [PubMed ID: 36721040]

  • Investigating the role of receptor interacting protein kinase 3 in venous thrombosis.
    DeRoo E, Khoury M, Zhou T, Yang H, Stranz A, Luke C, Henke P, Liu B
    JVS Vasc Sci 2022; 3: 365-378
    [PubMed ID: 36568281]

  • Stimuli-Responsive Polymer Coatings for the Rapid and Tunable Contact Transfer of Plasmid DNA to Soft Surfaces.
    Appadoo V, Carter MCD, Jennings J, Guo X, Liu B, Hacker TA, Lynn DM
    ACS Biomater Sci Eng 2022 Oct 10; 8(10): 4390-4401
    [PubMed ID: 36130280]

  • pH-Responsive Polyelectrolyte Coatings that Enable Catheter-Mediated Transfer of DNA to the Arterial Wall in Short and Clinically Relevant Inflation Times.
    Yu Y, Appadoo V, Ren J, Hacker TA, Liu B, Lynn DM
    ACS Biomater Sci Eng 2022 Oct 10; 8(10): 4377-4389
    [PubMed ID: 36121432]

  • Necroptosis is associated with Rab27-independent expulsion of extracellular vesicles containing RIPK3 and MLKL.
    Gupta K, Brown KA, Hsieh ML, Hoover BM, Wang J, Khoury MK, Pilli VSS, Beyer RSH, Voruganti NR, Chaudhary S, Roberts DS, Murphy RM, Hong S, Ge Y, Liu B
    J Extracell Vesicles 2022 Sep; 11(9): e12261
    [PubMed ID: 36063142]

All Publications on PubMed