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David P Foley, MD

Contact Dr. Foley

E-mail:
foley@surgery.wisc.edu

Phone:
(608) 263-9903

Mail:
600 HIGHLAND AVE
BX7375 CLINICAL SCIENCE CNTR-H4
MADISON, WI 53792-3284

David P Foley, MD

Associate Professor
Section of Liver and Kidney Surgery
Division of Transplantation
Program Director, Abdominal Transplant Surgery Fellowship

Education

  • MD, Boston University, 1994
  • General Surgery Residency, University of Massachusetts Medical School, 1994-2001
  • Surgical Research Fellowship, University of Massachusetts Department of Surgery, 1996-1998
  • Transplant Surgical Fellow, University of Wisconsin Hospital and Clinics, Madison, WI, 2001-2003

Professional Activities

Dr. Foley is involved with the following professional societies:

  • American Society of Transplant Surgeons
  • American Society of Transplantation
  • American Association for the Study of Liver Diseases
  • Association for Academic Surgery
  • Surgical Biology Club II
  • Society of University Surgeons
  • Central Surgical Association
  • Transplantation Society
  • Americas Hepato-Pancreato-Biliary Association
  • International Liver Transplant Society

Leadership Roles in Surgery and Transplantation

Dr. Foley has been very active in leadership positions in national surgical and transplant societies. He has served as Co-Chair for the Grants Review Committee for the American Society of Transplant Surgeons. He served on the Executive Committee for the Association for Academic Surgery and Co-Chair of the Education Committee. He has been the Co-Chair and Chair of the Executive Committee for the Liver and Intestine Community of Practice for the American Society of Transplantation.

Clinical Specialties

Dr. Foley is certified by the American Board of Surgery in General Surgery. Dr. Foley’s clinical focus is in liver and kidney transplantation. Dr. Foley provides a wide range of services including kidney transplant, laparoscopic donor nephrectomy, liver resection, and liver transplant.

Dr. Foley provides a wide range of services including Kidney Transplant, Laparoscopic Donor Nephrectomy, Liver Resection, Liver Transplant, and Wedge Resection of the Liver.

Research Interests

Dr. Foley’s clinical research interests include studying protective strategies to decrease organ damage and enhance organ function after kidney and liver transplantation. Dr. Foley focuses on identifying and modifying clinical risk factors that lead to poor liver function after liver transplantation. These include studying the use of older donor livers, livers recovered from donation after circulatory determination of death donors, and livers with steatosis. In addition, Dr. Foley leads clinical studies aimed at decreasing delayed kidney function after kidney transplantation.

Dr. Foley’s basic research efforts are focused on identifying novel protective strategies to minimize ischemia-reperfusion injury (IRI) in liver and kidney transplantation. More specifically, his laboratory investigates the cell-specific effects of augmenting endogenous antioxidant pathways in the setting of hepatic and renal IRI. Activation of these pathways in a cell-specific manner can decrease oxidative stress and may promote cellular recovery from these deleterious processes. The ultimate goal is to discover new pharmacologic therapies that can decrease IRI and improve organ function after kidney and liver transplantation.

Active Clinical Trials
  • A Phase 3, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of QPI-1002 for Prevention of Delayed Graft Function in Recipients of a Donation After Brain Death Older Donor Kidney Transplant
    Principal Investigator(s): David P Foley, MD
    Status: Recruiting
    [ClinicalTrials.gov: NCT02610296]
    More Information
  • A Randomized, Placebo-controlled, Prospective, Double-blind, Multicenter Phase 2/3 Study of the Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Recipients of a Donation After Brain Death Kidney Transplant
    Principal Investigator(s): David P Foley, MD
    Status: Recruiting
    [ClinicalTrials.gov: NCT02490202]
    More Information

Recent Publications
  • Does DCD donor time-to-death affect recipient outcomes? Implications of time-to-death at a high-volume center in the United States.
    Scalea JR, Redfield RR, Arpali E, Leverson GE, Bennett RJ, Anderson ME, Kaufman DB, Fernandez LA, D'Alessandro AM, Foley DP, Mezrich JD
    Am. J. Transplant. 2016 Jul 4.
    [PubMed ID: 27375072]
    More Information
  • Liver transplant outcomes using ideal donation after circulatory death livers are superior to using older donation after brain death donor livers.
    Scalea JR, Redfield RR, Foley DP
    Liver Transpl. 2016 Jun 17.
    [PubMed ID: 27314220]
    More Information
  • Cell-Specific Over-activation of Nrf2-mediated Gene Expression in Myeloid Cells Decreases Hepatic Ischemia Reperfusion Injury.
    Lee LY, Harberg C, Matkowskyj KA, Cook S, Roenneburg D, Werner S, Johnson DA, Johnson JA, Foley DP
    Liver Transpl. 2016 Apr 26.
    [PubMed ID: 27113842]
    More Information
  • Technical Aspects of Orthotopic Liver Transplantation for Hepatocellular Carcinoma.
    Lee LY, Foley DP
    Surg. Clin. North Am. 2016 Apr; 96(2):269-81.
    [PubMed ID: 27017864]
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  • Results of pediatric living donor compared to deceased donor liver transplantation in the PELD/MELD era: Experience from two centers on two different continents.
    Yankol Y, Fernandez LA, Kanmaz T, Leverson GE, Mezrich JD, Foley D, Mecit N, D'Alessandro AM, Acarli K, Kalayoglu M
    Pediatr Transplant 2016 Feb; 20(1):72-82.
    [PubMed ID: 26861217]
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  • Overactivation of the nuclear factor (erythroid-derived 2)-like 2-antioxidant response element pathway in hepatocytes decreases hepatic ischemia/reperfusion injury in mice.
    Lee LY, Harberg C, Matkowskyj KA, Cook S, Roenneburg D, Werner S, Johnson J, Foley DP
    Liver Transpl. 2016 Jan; 22(1):91-102.
    [PubMed ID: 26285140, PMC ID: 4718744]
    More Information
  • Keeping high model for end-stage liver disease score liver transplantation candidates alive.
    O'Leary JG, Orloff SL, Levitsky J, Martin P, Foley DP
    Liver Transpl. 2015 Nov; 21(11):1428-37.
    [PubMed ID: 26335696]
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  • Parathyroidectomy is underused in patients with tertiary hyperparathyroidism after renal transplantation.
    Lou I, Schneider DF, Leverson G, Foley D, Sippel R, Chen H
    Surgery 2016 Jan; 159(1):172-9.
    [PubMed ID: 26603850, PMC ID: 4688142]
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  • How Well Does Renal Transplantation Cure Hyperparathyroidism?
    Lou I, Foley D, Odorico SK, Leverson G, Schneider DF, Sippel R, Chen H
    Ann. Surg. 2015 Oct; 262(4):653-9.
    [PubMed ID: 26366545, PMC ID: 4576689]
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  • Renal Function and Transplantation in Liver Disease.
    Parajuli S, Foley D, Djamali A, Mandelbrot D
    Transplantation 2015 Sep; 99(9):1756-64.
    [PubMed ID: 26308413]
    More Information

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