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Dai  Yamanouchi, MD, PhD

Contact Dr. Yamanouchi


(608) 265-4420

600 Highland Ave
Madison, WI 53792

Dai Yamanouchi, MD, PhD

Associate Professor
Division of Vascular Surgery


  • MD, Gunma University, Japan, 2000
  • PhD, Gunma University, Japan, 2006
  • Surgical Internship and Residency, Gunma University Hospital, Japan, 2000-2003
  • Surgical Residency, Saiseikai Maebashi Hospital, Japan, 2001-2002
  • Research Fellowship, Nagoya University Graduate School of Medicine, Japan, 2003-2004
  • Clinical Fellowship in Vascular Surgery, Nagoya University Hospital, Japan, 2004-2007
  • Research Fellowship, Weill Cornell Medical College, New York, NY, 2007-2008
  • Fellowship in Advanced Endovascular Surgery, University of Wisconsin Madison, Madison, WI, 2009-2010

Clinical Specialties

Dr. Yamanouchi specializes in vascular and endovascular surgery. He is board certified in angiology and endovascular surgery in Japan.

Dr. Yamanouchi specializes in open and endovascular techniques for the treatment of vascular diseases. His expertise includes treatments for aortic aneurysms, carotid disease, aortic dissection, peripheral arterial disease, and other vascular disorders.

Dr. Yamanouchi provides a wide range of services including Abdominal Aortic Aneurysm (AAA) Repair - Endovascular, Abdominal Aortic Aneurysm (AAA) Repair - Open, Amputation, Angioplasty With Stent Placement, Carotid Endartecotomy, Carotid Stenting, Extended Efforts in Limb Salvage, Peripheral Artery Bypass, Thoracic Aortic Aneursym - Endovascular, Thoracic Aortic Aneursym - Open, Thoracic Outlet Syndrome Treatment, and Varicose Vein Treatment.

Research Interests

Dr. Yamanouchi’s research interests include the pathogenesis of abdominal aortic aneurysm and restenosis after angioplasty including balloon angioplasty and stent placement. He is also devoted to the development of novel materials for vascular bypass graft and gene delivery method to treat the patients who suffer peripheral arterial disease. In addition, Dr. Yamanouchi serves as principal investigator on a number of clinical trials.

Dr. Yamanouchi's Lab


Active Clinical Trials
  • A Multicenter, Open Label, Prospective, Non-randomized Study of the InCraft® Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSPIRATION)
    Principal Investigator(s): Dai Yamanouchi, MD, PhD
    Status: Active, not recruiting
    [ NCT01664078]
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  • Multicenter, Post-Market Study to Assess Outcomes of Patients Treated With the AFX System Compared to Other EVAR Devices for Endovascular Abdominal Aortic Aneurysm Repair: LEOPARD
    Principal Investigator(s): Dai Yamanouchi, MD, PhD
    Status: Enrolling by invitation
    [ NCT02407457]
    More Information

Recent Publications
  • Osteoclastogenesis in Abdominal Aortic Aneurysms: A new therapeutic target.
    Leung AD, Yamanouchi D
    Curr Drug Targets 2017 Sep 25.
    [PubMed ID: 28950811]
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  • Hyperglycemia attenuates receptor activator of NF-κB ligand-induced macrophage activation by suppressing insulin signaling.
    Kurihara C, Tanaka T, Yamanouchi D
    J. Surg. Res. 2017 Jun 15; 214():168-175.
    [PubMed ID: 28624040]
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  • Hyperglycemia Suppresses RANKL-Induced Osteoclast Differentiation through LXRβ Expression in RAW264.7 Cells.
    Tanaka T, Takei Y, Zaima N, Moriyama T, Yamanouchi D
    J. Nutr. Sci. Vitaminol. 2017; 63(1):28-34.
    [PubMed ID: 28367923]
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  • Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.
    Takei Y, Tanaka T, Kent KC, Yamanouchi D
    Arterioscler. Thromb. Vasc. Biol. 2016 Sep; 36(9):1962-71.
    [PubMed ID: 27386936]
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  • Hyperglycemia Suppresses Calcium Phosphate-Induced Aneurysm Formation Through Inhibition of Macrophage Activation.
    Tanaka T, Takei Y, Yamanouchi D
    J Am Heart Assoc 2016 Mar 28; 5(3):e003062.
    [PubMed ID: 27021877, PMC ID: 4943277]
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  • Inter-rater agreement and checklist validation for postoperative wound assessment using smartphone images in vascular surgery.
    Wiseman JT, Fernandes-Taylor S, Gunter R, Barnes ML, Saunders RS, Rathouz PJ, Yamanouchi D, Kent KC
    J Vasc Surg Venous Lymphat Disord 2016 Jul; 4(3):320-328.e2.
    [PubMed ID: 27318052, PMC ID: 4913032]
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  • Puerarin Suppresses Macrophage Activation via Antioxidant Mechanisms in a CaPO4-Induced Mouse Model of Aneurysm.
    Tanaka T, Moriyama T, Kawamura Y, Yamanouchi D
    J. Nutr. Sci. Vitaminol. 2016; 62(6):425-431.
    [PubMed ID: 28202848]
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  • Case Report of Percutaneous Retrograde Transcollateral Recanalization of the Superior Mesenteric Artery via the Celiac Artery for Acute Mesenteric Ischemia.
    Gupta PK, Smith BK, Yamanouchi D
    Medicine (Baltimore) 2015 Dec; 94(50):e2036.
    [PubMed ID: 26683911, PMC ID: 5058883]
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  • Postdischarge outcomes after endovascular abdominal aortic aneurysm repair.
    Gupta PK, Engelbert TL, Ramanan B, Fang X, Yamanouchi D, Hoch JR, Acher CW
    J. Vasc. Surg. 2014 Apr; 59(4):903-8.
    [PubMed ID: 24360236]
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  • Current status of medical treatment for abdominal aortic aneurysm.
    Kurosawa K, Matsumura JS, Yamanouchi D
    Circ. J. 2013; 77(12):2860-6.
    [PubMed ID: 24161907]
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