University of Wisconsin–Madison

Dai Yamanouchi, MD, PhD

Associate Professor

  • Division of Vascular Surgery
(608) 265-4420

600 Highland Ave
Madison, WI 53792


  • MD, Gunma University, Japan, 2000
  • PhD, Gunma University, Japan, 2006
  • Surgical Internship and Residency, Gunma University Hospital, Japan, 2000-2003
  • Surgical Residency, Saiseikai Maebashi Hospital, Japan, 2001-2002
  • Research Fellowship, Nagoya University Graduate School of Medicine, Japan, 2003-2004
  • Clinical Fellowship in Vascular Surgery, Nagoya University Hospital, Japan, 2004-2007
  • Research Fellowship, Weill Cornell Medical College, New York, NY, 2007-2008
  • Fellowship in Advanced Endovascular Surgery, University of Wisconsin Madison, Madison, WI, 2009-2010

Clinical Specialties

Dr. Yamanouchi specializes in vascular and endovascular surgery. He is board certified in angiology and endovascular surgery in Japan.

Dr. Yamanouchi specializes in open and endovascular techniques for the treatment of vascular diseases. His expertise includes treatments for aortic aneurysms, carotid disease, aortic dissection, peripheral arterial disease, and other vascular disorders.

Research Interests

Dr. Yamanouchi’s research interests include the pathogenesis of abdominal aortic aneurysm and restenosis after angioplasty including balloon angioplasty and stent placement. He is also devoted to the development of novel materials for vascular bypass graft and gene delivery method to treat the patients who suffer peripheral arterial disease. In addition, Dr. Yamanouchi serves as principal investigator on a number of clinical trials.

Dr. Yamanouchi’s Lab

Recent Publications:

    • Osteoclastogenesis in Abdominal Aortic Aneurysms: A new therapeutic target.
    • Leung AD, Yamanouchi D
    • Curr Drug Targets 2017 Sep 25;
    • [PubMed ID: 28950811]
    • Hyperglycemia attenuates receptor activator of NF-κB ligand-induced macrophage activation by suppressing insulin signaling.
    • Kurihara C, Tanaka T, Yamanouchi D
    • J. Surg. Res. 2017 Jun 15; 214: 168-175
    • [PubMed ID: 28624040]
    • Hyperglycemia Suppresses RANKL-Induced Osteoclast Differentiation through LXRβ Expression in RAW264.7 Cells.
    • Tanaka T, Takei Y, Zaima N, Moriyama T, Yamanouchi D
    • J. Nutr. Sci. Vitaminol. 2017; 63(1): 28-34
    • [PubMed ID: 28367923]
    • Osteoclastogenic Differentiation of Macrophages in the Development of Abdominal Aortic Aneurysms.
    • Takei Y, Tanaka T, Kent KC, Yamanouchi D
    • Arterioscler. Thromb. Vasc. Biol. 2016 Sep; 36(9): 1962-71
    • [PubMed ID: 27386936]
    • Hyperglycemia Suppresses Calcium Phosphate-Induced Aneurysm Formation Through Inhibition of Macrophage Activation.
    • Tanaka T, Takei Y, Yamanouchi D
    • J Am Heart Assoc 2016 Mar 28; 5(3): e003062
    • [PubMed ID: 27021877]

All Publications on PubMed