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Dixon Kaufman, MD, PhD, FACS

Contact Dr. Kaufman

E-mail:
kaufman@surgery.wisc.edu

Phone:
(608) 265-6471

Mail:
600 Highland Avenue
BX7375 CLINICAL SCIENCE CENTER
Madison, WI 53792

Fax:
(608) 262-6280

Dixon Kaufman, MD, PhD, FACS

Ray D. Owen Professor of Surgery
Chairman, Division of Transplantation
Section of Kidney and Pancreas Surgery

Education

  • MD, University of Minnesota, 1983
  • NIH National Research Service Award, 1986 – 1989
  • Surgery Internship and Residency, University of Minnesota, 1983 – 1991
  • Transplantation Fellowship, University of Minnesota, 1991 – 1992
  • PhD, University of Minnesota, 1994

Board Certifications

  • Fellow, American College of Surgeons, 1995
  • UNOS-Certified Primary Transplant Surgeon, Pancreas, 1993
  • Diplomate, American Board of Surgery, 1992

Professional Activities

Faculty Appointments:

  • Ray D. Owen Professor and Chief, Division of Transplantation, School of Medicine and Public Health, University of Wisconsin – Madision, 2011 – present
  • Director, Transplantation Service Line, University of Wisconsin Hospital and Clinics, Madison, WI, 2011 – present

Dr. Kaufman is involved with the following professional societies:

  • American Surgical Association
  • American Society of Transplant Surgeons
  • Association for Academic Surgery
  • Fellow, American College of Surgeons
  • Cell Transplant Society, Founding Member
  • Central Surgical Association
  • International Pancreas and Islet Association, Founding Member
  • Society of University Surgeons
  • The Surgical Biology Club I
  • Transplantation Society

Leadership Roles in Transplantation

Dr. Kaufman has held leadership positions in many facets of the transplant field. He has been very active with the American Society of Transplant Surgeons (ASTS) and has served as Chair of the Education Committee, the Executive Program Committee Chair for the American Transplant Congress, and on the Council of the ASTS. Dr. Kaufman is also very active with the United Network for Organ Sharing (UNOS). He was past Chair of the Pancreas/Islet Transplant Committee, served on the MPSC Committee and currently is Councilor of UNOS Region 7 and a member of the Executive Board. Dr. Kaufman is an associate editor for the American Journal of Transplantation, Transplantation Journal, and Clinical Transplantation Journal.

Clinical Specialties

Dr. Kaufman is certified by the American Board of Surgery in General Surgery. Dr Kaufman’s clinical focus has been on kidney, pancreas, and islet transplantation. He was the first pancreas transplant surgeon in North America to conduct and publish studies regarding steroid-free immunosuppression in pancreas transplantation, and the first to describe the use of alemtuzumab in pancreas transplants.

Research Interests

Dr. Kaufman’s experimental clinical research has focused on immunosuppression minimization in kidney transplant recipients, and human clinical trials of islet transplantatio. His basic research efforts have focused on development of a tolerance induction protocol in large animals. It is supported by an NIH UO-1 award as part of the Non-human Primate Tolerance Study Group Consortium.

Recent Publications
  • Antithymocyte globulin is associated with a lower incidence of de novo donor-specific antibodies in moderately sensitized renal transplant recipients.
    Brokhof MM, Sollinger HW, Hager DR, Muth BL, Pirsch JD, Fernandez LA, Bellingham JM, Mezrich JD, Foley DP, D'Alessandro AM, Odorico JS, Mohamed MA, Vidyasagar V, Ellis TM, Kaufman DB, Djamali A
    Transplantation 2014 Mar 27; 97(6):612-7.
    [PubMed ID: 24531846]
    More Information
  • Diagnosis and management of antibody-mediated rejection: current status and novel approaches.
    Djamali A, Kaufman DB, Ellis TM, Zhong W, Matas A, Samaniego M
    Am. J. Transplant. 2014 Feb; 14(2):255-71.
    [PubMed ID: 24401076]
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  • Knockdown of intraislet IKKβ by spherical nucleic acid conjugates prevents cytokine-induced injury and enhances graft survival.
    Rink JS, McMahon KM, Zhang X, Chen X, Mirkin CA, Thaxton CS, Kaufman DB
    Transplantation 2013 Nov 27; 96(10):877-84.
    [PubMed ID: 24247900, PMC ID: 3839058]
    More Information
  • Collagen IV-modified scaffolds improve islet survival and function and reduce time to euglycemia.
    Yap WT, Salvay DM, Silliman MA, Zhang X, Bannon ZG, Kaufman DB, Lowe WL, Shea LD
    Tissue Eng Part A 2013 Nov; 19(21-22):2361-72.
    [PubMed ID: 23713524, PMC ID: 3807710]
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  • Induction therapy in pancreas transplantation.
    Niederhaus SV, Kaufman DB, Odorico JS
    Transpl. Int. 2013 Jul; 26(7):704-14.
    [PubMed ID: 23672537]
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  • Serum β2-microglobulin at discharge predicts mortality and graft loss following kidney transplantation.
    Astor BC, Muth B, Kaufman DB, Pirsch JD, Michael Hofmann R, Djamali A
    Kidney Int. 2013 Oct; 84(4):810-7.
    [PubMed ID: 23657143]
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  • Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients.
    Djamali A, Muth BL, Ellis TM, Mohamed M, Fernandez LA, Miller KM, Bellingham JM, Odorico JS, Mezrich JD, Pirsch JD, D'Alessandro TM, Vidyasagar V, Hofmann RM, Torrealba JR, Kaufman DB, Foley DP
    Kidney Int. 2013 Jun; 83(6):1185-92.
    [PubMed ID: 23447068, PMC ID: 3672254]
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  • Potential role of mesenchymal stromal cells in pancreatic islet transplantation.
    Hematti P, Kim J, Stein AP, Kaufman D
    Transplant Rev (Orlando) 2013 Jan; 27(1):21-9.
    [PubMed ID: 23290684]
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  • Protein polymer hydrogels: effects of endotoxin on biocompatibility.
    Beenken-Rothkopf LN, Karfeld-Sulzer LS, Zhang X, Kissler H, Michie SA, Kaufman DB, Fontaine MJ, Barron AE
    J Biomater Appl 2013 Sep; 28(3):395-406.
    [PubMed ID: 22832218]
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  • Improvement in outcomes of clinical islet transplantation: 1999-2010.
    Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, Maffi P, Posselt A, Stock PG, Kaufman DB, Luo X, Kandeel F, Cagliero E, Turgeon NA, Witkowski P, Naji A, O'Connell PJ, Greenbaum C, Kudva YC, Brayman KL, Aull MJ, Larsen C, Kay TW, Fernandez LA, Vantyghem MC, Bellin M, Shapiro AM
    Diabetes Care 2012 Jul; 35(7):1436-45.
    [PubMed ID: 22723582, PMC ID: 3379615]
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