Education

• MD, New York University, School of Medicine, New York, NY, 1987
• Residency, General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 1987-1994
• Postdoctoral Research Fellow, Harrison Department of Surgical Research, Hospital of the University of Pennsylvania, Philadelphia, PA, 1990-1992
• Fellow, Transplant Surgery, University of Wisconsin Hospital and Clinics, Madison, WI, 1994-1996

Clinical Specialties

Dr. Odorico is certified by the American Board of Surgery. He specializes in pancreatic, islet cell, and multi-organ transplants.

Dr. Odorico provides a wide range of services including Kidney Transplant and Pancreas Transplant.

Research Interests

Dr. Odorico’s research focuses on stem cell biology and differentiation, developing novel stem cell-based strategies for treating diabetes, pancreas transplantation, and islet cell transplantation.

Dr. Odorico's Lab

Funding/Grants

• Determining the role of Ptf1a in pancreas specification and endocrine cell differentiation using an ESC in vitro model system
  Funding Agency: The University of Wisconsin
  Principal Investigator(s): Jon S Odorico, MD
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• Epigenetic control of reprogramming and differentiation to pancreatic beta cells
  Funding Agency: American Diabetes Association
  Principal Investigator(s): Jon S Odorico, MD
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Active Clinical Trials

• Islet Transplantation in Type 1 Diabetic Patients Using a Steroid-free Immunosuppression Protocol and Thiazolidinedione Insulin Sensitizers
  Principal Investigator(s): Jon S Odorico, MD
  Status: Active, not recruiting
  [ClinicalTrials.gov: NCT00214253]
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Recent Publications

• Induction therapy in pancreas transplantation.
  Niederhaus SV, Kaufman DB, Odorico JS
  Transpl. Int. 2013 Apr 30.
  [PubMed ID: 23672537]
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• Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients.
  Djamali A, Muth BL, Ellis TM, Mohamed M, Fernandez LA, Miller KM, Bellingham JM, Odorico JS, Mezrich JD, Pirsch JD, D'Alessandro TM, Vidyasagar V, Hofmann RM, Torrealba JR, Kaufman DB, Foley DP
  Kidney Int. 2013 Feb 27.
  [PubMed ID: 23447068]
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• Improvement in outcomes of clinical islet transplantation: 1999-2010.
  Barton FB, Rickels MR, Alejandro R, Hering BJ, Wease S, Naziruddin B, Oberholzer J, Odorico JS, Garfinkel MR, Levy M, Pattou F, Berney T, Secchi A, Messinger S, Senior PA, Maffi P, Posselt A, Stock PG, Kaufman DB, Luo X, Kandeel F, Cagliero E, Turgeon NA, Witkowski P, Naji A, O'Connell PJ, Greenbaum C, Kudva YC, Brayman KL, Aull MJ, Larsen C, Kay TW, Fernandez LA, Vantyghem MC, Bellin M, Shapiro AM
  Diabetes Care 2012 Jul; 35(7):1436-45.
  [PubMed ID: 22723582, PMC ID: 3379615]
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• Differential outcomes of expanded-criteria donor renal allografts according to recipient age.
  Mezrich JD, Pirsch JD, Fernandez LA, Foley DP, Bellingham JM, Odorico JS, Leverson GE, Munoz-Del-Rio A, Sollinger HW, Kaufman DB, D'Alessandro AM
  Clin J Am Soc Nephrol 2012 Jul; 7(7):1163-71.
  [PubMed ID: 22653256, PMC ID: 3386667]
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• Early metabolic markers that anticipate loss of insulin independence in type 1 diabetic islet allograft recipients.
  Hirsch D, Odorico J, Danobeitia JS, Alejandro R, Rickels MR, Hanson M, Radke N, Baidal D, Hullett D, Naji A, Ricordi C, Kaufman D, Fernandez L
  Am. J. Transplant. 2012 May; 12(5):1275-89.
  [PubMed ID: 22300172]
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