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Lee G Wilke, MD, FACS

Surgical Services

Contact Dr. Wilke


(608) 265-5852

600 Highland Avenue
Box 7375 Clinical Science Center
Madison, WI 53792

Lee G Wilke, MD, FACS

Interim Chair, Divisions of General Surgery
Director, UW Health Breast Center
Professor, Division of Surgical Oncology


  • MD, Duke University, Durham, NC, 1993
  • Residency in Surgery, University of Michigan, Ann Arbor, Michigan, 1993-2000
  • ACS Resident Research Fellow in Immunotherapy, University of Michigan, Ann Arbor, MI 1996-1998

Clinical Specialties

Dr. Wilke is certified by the American Board of Surgery and specializes in benign and malignant diseases of the breast; sentinel lymph-node mapping; neoadjuvant therapy for breast cancer; and oncoplastic breast surgery.

Dr. Wilke provides a wide range of services including Axillary Lymph Node Dissection, Core Needle Biopsy, Lumpectomy or Partial Mastectomy, Modified Radical Mastectomy, Needle-localized Biopsy, Needle-localized Excision, Sentinel Lymph Node Biopsy, Simple Mastectomy, and Skin-sparing and/or Nipple-sparing Mastectomy.

Research Interests

Dr. Wilke’s principal research interest is in clinical trials seeking novel methods of treating patients with breast cancer. Dr. Wilke is a member of the Commission on Cancer. She is also a collaborator on multiple grants and trials evaluating novel treatments for breast cancer.

Active Clinical Trials

Recent Publications
  • Mammography Screening: Gaps in Patient's and Physician's Needs for Shared Decision-Making.
    DuBenske LL, Schrager S, McDowell H, Wilke LG, Trentham-Dietz A, Burnside ES
    Breast J 2017 Mar; 23(2):210-214.
    [PubMed ID: 28252231]
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  • Breast Cancer Survivor Advocacy at a University Hospital: Development of a Peer Support Program with Evaluation by Patients, Advocates, and Clinicians.
    Mirrielees JA, Breckheimer KR, White TA, Denure DA, Schroeder MM, Gaines ME, Wilke LG, Tevaarwerk AJ
    J Cancer Educ 2017 Mar; 32(1):97-104.
    [PubMed ID: 26477478, PMC ID: 4837082]
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  • Fewer Reoperations After Lumpectomy for Breast Cancer with Neoadjuvant Rather than Adjuvant Chemotherapy: A Report from the National Cancer Database.
    Landercasper J, Bennie B, Parsons BM, Dietrich LL, Greenberg CC, Wilke LG, Linebarger JH
    Ann. Surg. Oncol. 2017 Jan 06.
    [PubMed ID: 28062931]
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  • Society of Surgical Oncology Breast Disease Working Group Statement on Prophylactic (Risk-Reducing) Mastectomy.
    Hunt KK, Euhus DM, Boughey JC, Chagpar AB, Feldman SM, Hansen NM, Kulkarni SA, McCready DR, Mamounas EP, Wilke LG, Van Zee KJ, Morrow M
    Ann. Surg. Oncol. 2017 Feb; 24(2):375-397.
    [PubMed ID: 27933411]
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  • Reexcision Surgery for Breast Cancer: An Analysis of the American Society of Breast Surgeons (ASBrS) Mastery(SM) Database Following the SSO-ASTRO "No Ink on Tumor" Guidelines.
    Schulman AM, Mirrielees JA, Leverson G, Landercasper J, Greenberg C, Wilke LG
    Ann. Surg. Oncol. 2017 Jan; 24(1):52-58.
    [PubMed ID: 27581607]
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  • Contralateral Prophylactic Mastectomy Consensus Statement from the American Society of Breast Surgeons: Additional Considerations and a Framework for Shared Decision Making.
    Boughey JC, Attai DJ, Chen SL, Cody HS, Dietz JR, Feldman SM, Greenberg CC, Kass RB, Landercasper J, Lemaine V, MacNeill F, Margenthaler JA, Song DH, Staley AC, Wilke LG, Willey SC, Yao KA
    Ann. Surg. Oncol. 2016 Oct; 23(10):3106-11.
    [PubMed ID: 27469118, PMC ID: 4999472]
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  • Contralateral Prophylactic Mastectomy (CPM) Consensus Statement from the American Society of Breast Surgeons: Data on CPM Outcomes and Risks.
    Boughey JC, Attai DJ, Chen SL, Cody HS, Dietz JR, Feldman SM, Greenberg CC, Kass RB, Landercasper J, Lemaine V, MacNeill F, Song DH, Staley AC, Wilke LG, Willey SC, Yao KA, Margenthaler JA
    Ann. Surg. Oncol. 2016 Oct; 23(10):3100-5.
    [PubMed ID: 27469117, PMC ID: 4999465]
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  • Oncologists' perceived barriers to an expanded role for primary care in breast cancer survivorship care.
    Neuman HB, Jacobs EA, Steffens NM, Jacobson N, Tevaarwerk A, Wilke LG, Tucholka J, Greenberg CC
    Cancer Med 2016 Sep; 5(9):2198-204.
    [PubMed ID: 27356781, PMC ID: 5055160]
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  • Current Trends in the Management of Phyllodes Tumors of the Breast.
    Adesoye T, Neuman HB, Wilke LG, Schumacher JR, Steiman J, Greenberg CC
    Ann. Surg. Oncol. 2016 Oct; 23(10):3199-205.
    [PubMed ID: 27334214, PMC ID: 5021443]
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  • Correlation of breast tissue histology and optical signatures to improve margin assessment techniques.
    Kennedy S, Caldwell M, Bydlon T, Mulvey C, Mueller J, Wilke L, Barry W, Ramanujam N, Geradts J
    J Biomed Opt 2016 Jun 01; 21(6):66014.
    [PubMed ID: 27327487, PMC ID: 4914603]
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