Education

• MD, Duke University, Durham, NC, 1993
• Residency in Surgery, University of Michigan, Ann Arbor, Michigan, 1993-2000
• ACS Resident Research Fellow in Immunotherapy, University of Michigan, Ann Arbor, MI 1996-1998

Clinical Specialties

Dr. Wilke is certified by the American Board of Surgery and specializes in benign and malignant diseases of the breast; sentinel lymph-node mapping; neoadjuvant therapy for breast cancer; and oncoplastic breast surgery.

Dr. Wilke provides a wide range of services including Axillary Lymph Node Dissection, Core Needle Biopsy, Lumpectomy or Partial Mastectomy, Modified Radical Mastectomy, Needle-localized Biopsy, Needle-localized Excision, Sentinel Lymph Node Biopsy, Simple Mastectomy, and Skin-sparing and/or Nipple-sparing Mastectomy.

Research Interests

Dr. Wilke’s principal research interest is clinical trials seeking novel methods of treating patients with breast cancer. Dr. Wilke is a member of the Commission on Cancer. She is also a collaborator on multiple grants and trials evaluating novel treatments for breast cancer.

Recent Publications

• Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast.
  Bydlon TM, Barry WT, Kennedy SA, Brown JQ, Gallagher JE, Wilke LG, Geradts J, Ramanujam N
  PLoS ONE 2012; 7(12):e51418.
  [PubMed ID: 23251526, PMC ID: 3519619]
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• Erratum to: Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways.
  Ibarra-Drendall C, Troch MM, Barry WT, Broadwater G, Petricoin EF, Wulfkuhle J, Liotta LA, Lem S, Baker JC, Ford AC, Wilke LG, Zalles C, Kuderer NM, Hoffman AW, Shivraj M, Mehta P, Williams J, Tolbert N, Lee LW, Pilie PG, Yu D, Seewaldt VL
  Breast Cancer Res. Treat. 2012 Oct; 135(3):925.
  [PubMed ID: 22936392]
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• Intraoperative imprint cytology and frozen section pathology for margin assessment in breast conservation surgery: a systematic review.
  Esbona K, Li Z, Wilke LG
  Ann. Surg. Oncol. 2012 Oct; 19(10):3236-45.
  [PubMed ID: 22847119]
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• Risk of invasive breast cancer and ductal carcinoma in situ in women with atypical papillary lesions of the breast.
  Cuneo KC, Dash RC, Wilke LG, Horton JK, Koontz BF
  Breast J 2012 Sep; 18(5):475-8.
  [PubMed ID: 22776070]
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• Impact of neoadjuvant chemotherapy on wound complications after breast surgery.
  Decker MR, Greenblatt DY, Havlena J, Wilke LG, Greenberg CC, Neuman HB
  Surgery 2012 Sep; 152(3):382-8.
  [PubMed ID: 22739071, PMC ID: 3432709]
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• Impact of axillary ultrasound and core needle biopsy on the utility of intraoperative frozen section analysis and treatment decision making in women with invasive breast cancer.
  Caretta-Weyer H, Sisney GA, Beckman C, Burnside ES, Salkowsi LR, Strigel RM, Wilke LG, Neuman HB
  Am. J. Surg. 2012 Sep; 204(3):308-14.
  [PubMed ID: 22483606]
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• Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers.
  Latosinsky S, Cheifetz RE, Wilke LG,
  J. Am. Coll. Surg. 2011 Sep; 213(3):447-50.
  [PubMed ID: 21871383]
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• Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways.
  Ibarra-Drendall C, Troch MM, Barry WT, Broadwater G, Petricoin EF, Wulfkuhle J, Liotta LA, Lem S, Baker JC, Ford AC, Wilke LG, Zalles C, Kuderer NM, Hoffman AW, Shivraj M, Mehta P, Williams J, Tolbert N, Lee LW, Pilie PG, Yu D, Seewaldt VL
  Breast Cancer Res. Treat. 2012 Apr; 132(2):487-98.
  [PubMed ID: 21647677, PMC ID: 3638770]
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• Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.
  Pilie PG, Ibarra-Drendall C, Troch MM, Broadwater G, Barry WT, Petricoin EF, Wulfkuhle JD, Liotta LA, Lem S, Baker JC, Stouder A, Ford AC, Wilke LG, Zalles CM, Mehta P, Williams J, Shivraj M, Su Z, Geradts J, Yu D, Seewaldt VL
  Cancer Epidemiol. Biomarkers Prev. 2011 Mar; 20(3):476-82.
  [PubMed ID: 21242333, PMC ID: 3051011]
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• Early results from a novel quality outcomes program: the American Society Of Breast Surgeons' Mastery of Breast Surgery.
  Clifford EJ, De Vol EB, Pockaj BA, Wilke LG, Boughey JC
  Ann. Surg. Oncol. 2010 Oct; 17 Suppl 3():233-41.
  [PubMed ID: 20853039]
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