Lee G Wilke, MD, FACS


  • Senior Medical Director, Clinical Cancer Services; UW Health/UW Carbone Cancer Center
  • Professor, Division of Surgical Oncology
  • Hendricks Chair in Breast Cancer Surgery Research

(608) 263-7064

  • Administrative Assistant: (608) 262-2025

600 Highland Avenue
Box 7375 Clinical Science Center
Madison, WI 53792


  • MD, Duke University, Durham, NC
  • Residency in Surgery, University of Michigan, Ann Arbor, Michigan
  • ACS Resident Research Fellow in Immunotherapy, University of Michigan, Ann Arbor, MI

Clinical Specialties

Dr. Wilke is certified by the American Board of Surgery and specializes in benign and malignant diseases of the breast; sentinel lymph-node mapping; neoadjuvant therapy for breast cancer; and oncoplastic breast surgery.

Research Interests

Dr. Wilke’s principal research interest is in clinical trials seeking novel methods of treating patients with breast cancer. Dr. Wilke is lead Principal investigator for the UW Carbone Cancer Center NCTN Lead Academic Program UG1 Grant and a Board member for the NCCN and NAPBC. She is a collaborator on multiple grants and trials evaluating novel medical and surgical treatments for breast cancer.

Recent Publications

  • Validation of the AJCC 8th Edition Breast Cancer Prognostic Staging System in Legacy Alliance Trials (AFT-01).
    Krecko LK, Neuman HB, Greenberg CC, Wilke LG, Hanlon BM, Edge SB, Ruddy KJ, Partridge AH, Le-Rademacher J, Yang DY, Havlena J, R Schumacher J
    Ann Surg Oncol 2024 Jun 02;
    [PubMed ID: 38825628]

  • A Four-Arm Randomized Clinical Trial of Topical Pain Control for Sentinel Node Radiotracer Injections in Patients with Breast Cancer.
    Wiener AA, Schumacher JR, Perlman SB, Wilke LG, Lautner MA, Bozzuto LM, Hanlon BM, Neuman HB
    Ann Surg Oncol 2024 Apr 01;
    [PubMed ID: 38557909]

  • Transforming the Future of Surgeon-Scientists.
    Ladner DP, Goldstein AM, Billiar TR, Cameron AM, Carpizo DR, Chu DI, Coopersmith CM, DeMatteo RP, Feng S, Gallagher KA, Gillanders WE, Lal BK, Lipshutz GS, Liu A, Maier RV, Mittendorf EA, Morris AM, Sicklick JK, Velazquez OC, Whitson BA, Wilke LG, Yoon SS, Zeiger MA, Farmer DL, Hwang ES, ASA Task Force for Research Sustainability
    Ann Surg 2024 Feb 01; 279(2): 231-239
    [PubMed ID: 37916404]

  • Surgeon or Bot? The Risks of Using Artificial Intelligence in Surgical Journal Publications.
    Shaffrey EC, Eftekari SC, Wilke LG, Poore SO
    Ann Surg Open 2023 Sep; 4(3): e309
    [PubMed ID: 37746615]

  • Reexamining Time From Breast Cancer Diagnosis to Primary Breast Surgery.
    Wiener AA, Hanlon BM, Schumacher JR, Vande Walle KA, Wilke LG, Neuman HB
    JAMA Surg 2023 May 01; 158(5): 485-492
    [PubMed ID: 36857045]

All Publications on PubMed