Education

• M.D, University of Wisconsin Medical School, Madison, WI, 1993
• Residency in General Surgery, University of Wisconsin Hospital and Clinics, Madison, WI, 1993-1999
• Research Fellowship in Tumor Immunotherapy, University of Wisconsin Medical School, Madison, WI, 1996-1997
• Surgical Oncology Fellowship, Memorial Sloan-Kettering Cancer Center, New York, NY, 1999-2001
• Hepatobiliary Fellowship, Memorial Sloan-Kettering Cancer Center, New York, NY, 2000-2001

Clinical Specialties

Dr Sharon Weber trained at Memorial Sloan-Kettering Cancer Center, with dual fellowships in surgical oncology and hepatobiliary. She specializes in benign and malignant disorders of the liver, pancreas and bile duct, in addition to gastric cancer, melanoma and sarcoma. Dr Weber is actively involved in minimally invasive approaches to cancer treatment, including both laparoscopic pancreas and liver surgery. She has been invited as a speaker/moderator at many national meetings, including the American College of Surgeons, the American Hepatopancreaticobiliary Association, Society of Surgical Oncology, and Society of University Surgeons. She is currently the chief of the Surgical Oncology and the Chief of Surgery at the William S. Middleton VA.

Dr. Weber provides a wide range of services including Bile Duct Resection, Caudate Resection, Cryoablation, Cyst Fenestration (Unroof Liver Cyst), Frey Procedure, Gastrectomy - Partial or Total, Hemihepatectomy (Hepatectomy), Laparoscopic Liver Resection, Laparoscopic Pancreatectomy, Liver Resection, Liver Tumor Ablations, Melanoma Completion Lymph Node Dissection (Axillary and Groin), Melanoma Sentinel Lymph Node Biopsy, Melanoma Wide Local Excision and Skin Closure, Obstructed Pancreatic Duct Drainage (Peustow Procedure), Pancreatic Head Resection, Pancreaticoduodenectomy, Pancreatic Pseudocysts Drainage, Pancreatic Resections, Radical Cholecystectomy, (show all). Radiofrequency Ablation, Right Hemihepatectomy, Right / Left Extended Hemihepatectomy (Hepatectomy), Wedge Resection of the Liver, and Whipple Procedure.

Research Interests

Dr. Weber conducts translational research at the UW Carbone Cancer Center evaluating novel tumor selective agents which may be promising for imaging and/or treating tumors. She also conducts clinical research evaluating prognosticators of outcome in patients with liver, bile duct, and liver tumors. She also conducts outcomes research evaluating preoperative predictors of postoperative complications for patients undergoing pancreatectomy.

Active Clinical Trials

• A Phase II Study of Preoperative Gemcitabine and Erlotinib Plus Pancreatectomy and Postoperative Gemcitabine and Erlotinib for Patients With Operable Pancreatic Adenocarcinoma
  Principal Investigator(s): Sharon M Weber, MD
  Status: Recruiting
  [ClinicalTrials.gov: NCT00733746]
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• A Prognostic Study of Sentinel Node and Bone Marrow Micrometastases in Women With Clinical T1-2 N0 Breast Cancer
  Principal Investigator(s): Sharon M Weber, MD
  Status: Active, not recruiting
  [ClinicalTrials.gov: NCT00003854]
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• A Randomized, Open Label, Parallel-group, Multi-center Trial to Compare the Efficacy and Safety of TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery
  Principal Investigator(s): Sharon M Weber, MD
  Status: Recruiting
  [ClinicalTrials.gov: NCT01192022]
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• A Randomized Trial of Axillary Node Dissection in Women With Clinical T1-2 N0-1 M0 Breast Cancer Who Have a Positive Sentinel Node
  Principal Investigator(s): Sharon M Weber, MD
  Status: Active, not recruiting
  [ClinicalTrials.gov: NCT00003855]
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Recent Publications

• Multi-institutional analysis of pancreatic adenocarcinoma demonstrating the effect of diabetes status on survival after resection.
  Cannon RM, LeGrand R, Chagpar RB, Ahmad SA, McClaine R, Kim HJ, Rupp C, Cho CS, Brinkman A, Weber S, Winslow ER, Kooby DA, Chu CK, Staley CA, Glenn I, Hawkins WG, Parikh AA, Merchant NB, McMasters KM, Martin RC, Callender GG, Scoggins CR
  HPB (Oxford) 2012 Apr; 14(4):228-35.
  [PubMed ID: 22404260]
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• Educational value of morbidity and mortality (M&M) conferences: are minor complications important?
  Thomas MK, McDonald RJ, Foley EF, Weber SM
  J Surg Educ 2012 May-Jun; 69(3):326-9.
  [PubMed ID: 22483132]
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• Laparoscopic versus open left pancreatectomy: can preoperative factors indicate the safer technique?
  Cho CS, Kooby DA, Schmidt CM, Nakeeb A, Bentrem DJ, Merchant NB, Parikh AA, Martin RC, Scoggins CR, Ahmad SA, Kim HJ, Hamilton N, Hawkins WG, Weber SM
  Ann. Surg. 2011 May; 253(5):975-80.
  [PubMed ID: 21394014]
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• Alcohol dose effects on stress response to cued threat vary by threat intensity.
  Moberg CA, Weber SM, Curtin JJ
  Psychopharmacology (Berl.) 2011 Nov; 218(1):217-27.
  [PubMed ID: 21503605]
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• Preoperative factors predict perioperative morbidity and mortality after pancreaticoduodenectomy.
  Greenblatt DY, Kelly KJ, Rajamanickam V, Wan Y, Hanson T, Rettammel R, Winslow ER, Cho CS, Weber SM
  Ann. Surg. Oncol. 2011 Aug; 18(8):2126-35.
  [PubMed ID: 21336514]
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