David Harris, MD

Assistant Professor

daharris6@wisc.edu
(608) 263-1036

WIMR 5131
1111 Highland Avenue

Education

  • MD, University of Virginia
  • Residency, Brigham and Women's Hospital & Harvard Medical School, General Surgery
  • Fellowship, Brigham and Women's Hospital & Harvard Medical School, Advanced GI & Bariatric Surgery

Dr. Harris provides a wide range of services including Laparoscopic Revisional Bariatric Surgery.

Research Interests

Dr. Harris’ Lab, the Wisconsin Surgical Laboratory in Metabolism (WiSLiM), studies the mechanistic intersection between metabolic therapies, host metabolism, organ function, and aging.

Dr. Harris received a one-year pilot grant from Washington University’s Diabetes Research Center to explore potential treatments for Type 2 diabetes. Read more here.

Dr. Harris received a one-year, 30,000 pilot award from the Center for Biomedical Swine Research & Innovation. Read more here.

Dr. Harris received pilot award funding from the Wisconsin Alumni Research Foundation. Read more here.

Dr. Harris was recently awarded a two-year, $311,000 grant from the National Institute on Aging. Read more here.

Dr. Harris received a two-year, $80,000 Research Education Component Scholar award from the Wisconsin Alzheimer’s Disease Research Center. Read more here.

Dr. Harris received a one-year, $67,000 Fall Research Competition award from the Office of the Vice Chancellor for Research. Read more here.

Dr. Harris received a two-year, $150,000 New Investigator Program award from the Wisconsin Partnership Program. Read more here.

Recent Publications

  • Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease.
    Hagemann TL, Sonsalla MM, Luzinski C, Zacahua F, Harris DA, Lamming DW, Messing A
    Ann Clin Transl Neurol 2025 Sep 29;
    [PubMed ID: 41024483]

  • The GLP-1 Era-What Comes After Bariatric Surgery?
    Lauer KV, Harris DA, Funk LM
    JAMA Surg 2025 Oct 01; 160(10): 1066-1067
    [PubMed ID: 40864450]

  • Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease.
    Babygirija R, Han JH, Sonsalla MM, Matoska R, Calubag MF, Green CL, Tobon A, Yeh CY, Vertein D, Schlorf S, Illiano J, Liu Y, Grunow I, Rigby MJ, Puglielli L, Harris DA, Denu JM, Lamming DW
    Nat Commun 2025 Aug 04; 16(1): 7147
    [PubMed ID: 40759886]

  • Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids.
    Calubag MF, Ademi I, Grunow ID, Breuer LE, Babygirija R, Lialios P, Le SM, Sonsalla MM, Illiano JA, Knopf BA, Xiao F, Minton D, Konopka AR, Harris DA, Lamming DW
    Aging Cell 2025 Oct; 24(10): e70176
    [PubMed ID: 40726002]

  • Tissue-specific effects of dietary protein on cellular senescence are mediated by branched-chain amino acids.
    Calubag MF, Ademi I, Grunow I, Breuer L, Babygirija R, Lialios P, Le S, Minton D, Sonsalla MM, Illiano J, Knopf BA, Xiao F, Konopka AR, Harris DA, Lamming DW
    bioRxiv 2025 Jan 16;
    [PubMed ID: 39868338]

All Publications on PubMed