University of Wisconsin–Madison

Joshua D Mezrich, MD

Associate Professor

  • Section of Liver and Kidney Surgery
  • Division of Transplantation
(608) 263-2527

600 Highland Ave.
MC 7375
Madison, WI 53792-3284


  • MD, Cornell University Medical College, 1997
  • Surgery Residency, University of Chicago Hospitals, Chicago, IL, 1997-2005
  • Research Fellowship, Transplantation Biology Research Center, Massachusetts General Hospital, Boston, MA
  • Transplantation Fellowship, University of Wisconsin Hospital and Clinics, Madison, WI, 2005-2007

Clinical Specialties

Dr. Mezrich is certified by the American Board of Surgery. He specializes in solid organ transplant (liver, kidney, and pancreas).

Dr. Mezrich provides a wide range of services including Kidney Transplant, Laparoscopic Donor Nephrectomy, Liver Resection, Liver Transplant, Wedge Resection of the Liver, “Scarless” Single-Port Laparoscopic Donor Nephrectomy.

Research Interests

Dr. Mezrich’s research interest is in transplant tolerance and how environmental exposures alter the immune system.

Recent Publications

    • The gut symbionts Lactobacillus reuteri R2lc and 2010 encode a polyketide synthase cluster that activates the mammalian aryl-hydrocarbon receptor.
    • Özçam M, Tocmo R, Oh JH, Afrazi A, Mezrich JD, Roos S, Claesen J, van Pijkeren JP
    • Appl. Environ. Microbiol. 2018 Nov 02;
    • [PubMed ID: 30389766]
    • Ambient urban dust particulate matter reduces pathologic T cells in the CNS and severity of EAE.
    • O'Driscoll CA, Owens LA, Hoffmann EJ, Gallo ME, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD
    • Environ. Res. 2019 Jan; 168: 178-192
    • [PubMed ID: 30316103]
    • Differential effects of diesel exhaust particles on T cell differentiation and autoimmune disease.
    • O'Driscoll CA, Owens LA, Gallo ME, Hoffmann EJ, Afrazi A, Han M, Fechner JH, Schauer JJ, Bradfield CA, Mezrich JD
    • Part Fibre Toxicol 2018 08 24; 15(1): 35
    • [PubMed ID: 30143013]
    • Specific Donor HLA-DR Types Correlate With Altered Susceptibility to Development of Chronic Lung Allograft Dysfunction.
    • Haynes LD, Julliard WA, Mezrich JD, Leverson G, Meyer KC, Burlingham WJ
    • Transplantation 2018 Jul; 102(7): 1132-1138
    • [PubMed ID: 29360666]
    • Renal Transplantation as a Platform for Teaching Residents Open Vascular Surgical Techniques: Effects on Early Graft Function.
    • Grodstein EI, Little C, Molmenti EP, Mezrich JD
    • J Surg Educ 2018 Jul - Aug; 75(4): 964-967
    • [PubMed ID: 29361509]

All Publications on PubMed