Dr. Ronnekleiv-Kelly’s Lab

Our Goals

To understand how the Per-Arnt-Sim family of ‘environmental sensor’ proteins impacts aggressive cancers including pancreatic cancer and Fibrolamellar carcinoma; and to exploit this class of proteins for therapeutic effect.

Our Projects

1. Understanding how circadian biology plays a role in pancreas cancer and how circadian rhythm disruption contributes to pancreatic cancer development and spread.
2. Evaluating the extent to which the aryl hydrocarbon receptor impacts immune cell infiltration in the pancreatic cancer microenvironment and shapes the developing tumor.
3. Building unique models for understanding Fibrolamellar carcinoma development and identifying efficacious therapies.

Make a Donation

Support the Dr. Ronnekleiv-Kelly Research Lab through the UW-Madison Department of Surgery. Philanthropic gifts make a tremendous difference in advancing groundbreaking research.