Sara Dutton Sackett and Jon Odorico with visiting Australian scientist, Nathan Zammit.
Samantha Mitchell, Dan Tremmel and Vansh Jain are establishing new imaging protocols in the Small Animal Imaging Facility.
Dan Tremmel presentation at IPITA in Lyon, France - July, 2019.
Dan Tremmel, graduate student and Samantha Mitchell, research assistant.
JDRF Gala research tour recipients getting some first hand experience for how stem cells become insulin producing cells.
Andrew Curran presenting his poster at the 2018 Department of Surgery Research Symposium.
Austin Feeney presenting his poster at the 2018 Department of Surgery Research Symposium.
Sara Dutton Sackett, Dan Tremmel and Austin Feeney having fun in Lyon, France.
Marina Ignatowski presenting her poster at the 2018 Department of Surgery Research Symposium.
Left to right: Jon Odorico, MD; Austin Feeney, MD, PhD; Dan Tremmel, Research Assistant; Sara Dutton Sackett, PhD (missing: Sam Mitchell, Research Specialist).
Sara Dutton Sackett, PhD.
Confocal image of a pancreatic organoid highlighting the vascularization throughout the organoid construct of the human vascular endothelial cells (RED)
Pancreatic islet organoids in a 6-well plate. You can see the circular organoids floating with nicely defined edges and 50 IEQ human deceased donor islets embedded per organoid.
Pancreatic islet organoids “gelling” in a petri dish. After three days in culture, we will transplant these islet organoids subcutaneously into mice and track engraftment and vascularization.
Nate Jurrens, Caterra Leavens, Connie Chamberlain, and Deep Kapadia participating in Millipore Sigma's Googly Eye Day in the lab.
Connie Chamberlain, Caterra Leavens, and Ellen Abad Santos successfully completed a day of kidney subcapsular transplants. Stem cell-derived islet clusters were transplanted into immunodeficient mice to monitor the cells’ ability to reverse diabetes.
Deep Kapadia presenting his research on islet transplantation at the 2025 Annual Department of Surgery Research Summit.
Caterra Leavens and Dr. Jon Odorico at the 2025 Annual Department of Surgery Research Summit. Caterra was presenting a poster on her work with immune-evasive stem cell-derived pancreatic islet cells and won a best poster award!
Stem cell–derived pancreatic islets under attack in co-culture with activated T cells.
2024 Odorico Lab Photo (left top to bottom right): Dr. Jon Odorico, Dr. Connie Chamberlain, Andrew L., Deep K., Peter C., Palak D., Kayla T., Caterra L.
The Odorico lab exploring Boston during the 5th IPITA-sponsored Stem Cell-derived Islet Summit held on Harvard’s campus.
Dr. Dan Tremmel, Dr. Jon Odorico, Caterra Leavens, and Dr. Connie Chamberlain at the 5th IPITA-sponsored Stem Cell-derived Islet Summit at Harvard Medical School.
Graduate student, Caterra Leavens, presenting her research at the 5th IPITA-sponsored Stem Cell-derived Islet Summit held on the Harvard University campus.
Dr. Connie Chamberlain, Ellen Abad Santos, Katherine Gorski, and Caterra Leavens representing the Odorico lab at the 2024 Midwest Islet Conference (MIC) in Chicago.
Stem cell–derived pancreatic islets under attack in co-culture with activated T cells.
Stem cell-derived pancreatic islet -like clusters. In the lab, we call them potatoes!!
Caterra presenting her research proposal at her preliminary examination during the summer of 2025! She passed!
Palak Dhiman, an undergraduate student, presenting findings from her semester-long research project on islet vascularization conducted in the laboratory.
Andrew Li (undergraduate student), Dr. Odorico, and Deep Kapadia (Research Specialist) at the 2025 Annual Department of Surgery Research Summit.
In 2025, Palak Dhiman was honored with the Biochemistry Undergraduate Summer Research Award, through which she advanced her investigations into pancreatic organoid vascularization and its role in pancreatic islet cell biology.
Our laboratory employs a 32-day differentiation protocol to derive stem cell islet-like clusters (SCILCs), which are capable of producing insulin and represent a potential avenue toward a functional cure for diabetes.
