Department of Surgery
University of Wisconsin School of Medicine and Public Health

Publications

Publications
  1. Yang D, Cho H, Tayyebi Z, Shukla A, Luo R, Dixon G, Ursu V, Stransky S, Tremmel DM, Sackett SD, Koche R, Kaplan SJ, Li QV, Park J, Zhu Z, Rosen BP, Pulecio J, Shi ZD, Bram Y, Schwartz RE, Odorico JS, Sidoli S, Wright CV, Leslie CS, Huangfu D. CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nat Cell Biol. 2022 Jul;24(7):1064-1076. doi: 10.1038/s41556-022-00946-4. Epub 2022 Jul 4. PMID: 35787684
  2. Tremmel DM, Sackett SD, Feeney AK, Mitchell SA, Schaid MD, Polyak E, Chlebeck PJ, Gupta S, Kimple ME, Fernandez LA, Odorico JS. A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment. Sci Rep. 2022 May 3;12(1):7188. doi: 10.1038/s41598-022-11085-z. PMID: 35504932 Free PMC article.
  3. Tabang DN, Cui Y, Tremmel DM, Ford M, Li Z, Sackett SD, Odorico JS, Li L. Analysis of pancreatic extracellular matrix protein post-translational modifications via electrostatic repulsion-hydrophilic interaction chromatography coupled with mass spectrometry. Mol Omics. 2021 Oct 11;17(5):652-664. doi: 10.1039/d1mo00104c. PMID: 34318855 Free PMC article.
  4. Li Z, Tremmel DM, Ma F, Yu Q, Ma M, Delafield DG, Shi Y, Wang B, Mitchell SA, Feeney AK, Jain VS, Sackett SD, Odorico JS, Li L. Proteome-wide and matrisome-specific alterations during human pancreas development and maturation. Nat Commun. 2021 Feb 15;12(1):1020. doi: 10.1038/s41467-021-21261-w. PMID: 33589611 Free PMC article.
  5. Tremmel DM, Feeney AK, Mitchell SA, Chlebeck PJ, Raglin SA, Fernandez LA, Odorico JS, Sackett SD. Hypertension, but not body mass index, is predictive of increased pancreatic lipid content and islet dysfunction. Am J Transplant, 2019 Nov 12. doi: 10.1111/ajt.15698. [Epub ahead of print] PMID:31715064.
  6. Tremmel DM, Mitchell SA, Sackett SD, Odorico JS. Mimicking nature-made beta cells: recent advances towards stem cell-derived islets Curr Opin Organ Transplant. 2019 Oct;24(5):574-581. doi: 10.1097/MOT.0000000000000687.PMID:31433306
  7. Ma F, Tremmel DM, Li Z, Lietz CB, Sackett SD, Odorico JS, Li L. In depth quantification of extracellular matrix proteins from human pancreas. J Proteome Res. 2019 Aug 2;18(8):3156-3165. doi: 10.1021/acs.jproteome.9b00241. Epub 2019 Jul 1. PMID:31200599
  8. Tremmel DM, Odorico JS: Rebuilding a better home for transplanted islets. 2018. Dec; 14 (4):163-168. PMID 30252586
  9. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D’Amour , Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A: Report of the Key Opinion Leaders Meeting on Stem Cell-derivedBeta Cells. 2018 Aug; 102(8):1223-1229. PMID: 29781950
  10. Sackett SD, Tremmel DM, Ma F, Feeney AK, Maguire RM, Brown ME, Zhou Y, Li X, O’Brien C, Li L, Burlingham WJ, Odorico JS. Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas. Sci Rep. 2018 Jul 11; 8(1): 10452. PMID29993013
  11. Ma F, Sun R, Tremmel DM, Sackett SD, Odorico JS, Li L. Large-scale differentiation and site specific discrimination of hydroxyproline isomers by electron transfer/high-energy collision dissociation (EThcD) Mass Spectrometry. Anal Chem, 2018 May; 90(9):5857-5864. PMID: 29624053
  12. Sackett SD, Rodriguez A, Odorico JS: The Nexus of Stem Cell-derived Beta Cells and Genome Engineering. Rev Diabet Stud. 14(1):39-50, 2017, PMID:28632820.
  13. Odorico JS: Interspecies Organogenesis-Derived Tissues for Transplantation. Transplantation. 101(7):1510-1512, 2017.PMID: 28640012.
  14. Sackett SD, Brown ME, Tremmel DM, Ellis T, Burlingham WJ, Odorico JS: Modulation of human allogeneic and syngeneic pluripotent stem cells and immunological implications for transplantation. Transplant Rev (Orlando). 30(2):61-70, 2016. PMID:26970668.
  15. Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, OʼConnell P, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Kovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Report from IPITA-TTS Opinion Leaders Meeting on the Future of Beta cell Replacement. 2016 Feb;100 Suppl 2:S1-44. PMID:26840096.
  16. Markmann JF, Bartlett ST, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, Cooper DK, Park CG, OʼConnell PJ, Stabler C, Matsumoto S, Ludwig B, Choudhary P, Khovatchev B, Rickels MR, Sykes M, Wood K, Kraemer K, Hwa A, Stanley E, Ricordi C, Zimmerman M, Greenstein J, Montanya E, Otonkoski T. Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of Beta Cell Replacement. Transplantation. 2016 Jul;100(7):e25-31. PMID: 27082827.
  17. Nair G, Odorico J. Ptf1a activity in enriched posterior foregut endoderm, but not definitive endoderm, leads to enhanced pancreatic differentiation in an in vitro ES-based model. Stem Cells International. doi: 10.1155/2016/6939438. PMID: 27066080.
  18. Nair G, Vincent RK, Odorico JS. Ectopic Ptf1a expression in murine ESCs potentiates endocrine differentiation and models pancreas development in vitro.  Stem Cells.  32(5):1195-207. PMID:24375815.
Chapters
  1. Sackett SD, Tremmel DM, Feeney AK, Mitchell SA, Odorico JS. Human embryonic stem cells as a source of insulin-producing tissue. In Transplantation, bioengineering and Regeneration of the Endocrine Pancreas, Vol 1 and 2, eds. Orlando, Gruessner, Piemonti, Stratta, Ricordi, In press.
  2. Xu X, Browning V, Odorico J: Culture protocols for producing definitive endoderm and pancreatic lineage cells from human ES or iPS cells. Methods in Bioengineering, eds. M. Yarmush, R. Langer, Artech House, Boston, 2011.
Books
  1. Odorico JS, Zhang SC, Pedersen RA (eds.) Human Embryonic Stem Cells, Garland Science/BIOS Scientific Publishers, Oxford, 2005.