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Authors Frydman J, Bianco J, Drezner M, Chen H
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Journal Clin Nucl Med Volume: 29 Issue: 9 Pages: 542-4
Publish Date 2004 Sep
PubMed ID 15311119

Although bilateral exploration is highly effective in the treatment of primary hyperparathyroidism, minimally invasive parathyroidectomy has evolved into the procedure of choice when a single parathyroid lesion can be localized preoperatively. In this article, we discuss the utilization of thallium-pertechnetate subtraction scanning (TPSS) after technetium Tc-99m sestamibi scintigraphy failed to localize an ectopic parathyroid adenoma. Subsequently, radioguided resection of an undescended parathyroid adenoma inferior to the left submandibular gland was performed with surgical cure after a single procedure. This case report illustrates the importance of TPSS as a second-line modality in preoperative adenoma localization, thereby using minimally invasive techniques to successfully treat this patient’s primary hyperparathyroidism. Copyright © 2016 The Board of Regents of the University of Wisconsin System