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Authors Warner TF, Ford CN, Hafez GR
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Journal J. Cutan. Pathol. Volume: 12 Issue: 6 Pages: 520-7
Publish Date 1985 Dec
PubMed ID 4078112

Neurotropic melanoma is a variant of desmoplastic melanoma which, in addition to a spindle-cell vertical component and fibrosis, exhibits a fascicular growth pattern and invades cutaneous nerves. Here we describe a neurotropic melanoma which arose in a small lentigo maligna melanoma and invaded the maxillary nerve for a distance of 5 cm. Ultrastructural features were similar to those of previously described neurotropic melanomas and tumor fascicles contained S-100 protein and neuron-specific enolase immunoreactivity. Copyright © 2017 The Board of Regents of the University of Wisconsin System