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Authors Stewart CA, Cerhan J
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Journal Metab Brain Dis Volume: 20 Issue: 3 Pages: 193-204
Publish Date 2005 Sep
PubMed ID 16167197

Hepatic encephalopathy (HE) is a neuropsychiatric disorder associated with portal hypertension. The mechanism of this disorder is still being characterized and the management has relied primarily on lowering the amount of ammonia present in the gastrointestinal tract or reversing liver disease by replacing the diseased liver. It is, however, not established that all the effects of hepatic encephalopathy are reversed by liver transplantation. In this review, we have outlined the mechanisms underlying HE and the pros and cons of reversibility of HE. Copyright © 2017 The Board of Regents of the University of Wisconsin System