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Authors Vogler SA, Fenton SJ, Scaife ER, Book LS, Jackson D, Nichol PF, Meyers RL
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Journal J. Pediatr. Surg. Volume: 43 Issue: 6 Pages: 1006-10
Publish Date 2008 Jun
PubMed ID 18558174

In infants with gastroschisis antenatal closure of the umbilical defect results in a proximal atresia with ischemia and/or volvulus of the extracorporeal midgut. It has been described as “closed gastroschisis” or “vanishing midgut.”A 10-year review of 219 gastroschisis patients identified 10 infants with this rare complication.In these 10 infants, the extracorporeal midgut was invariably matted and fibrosed. In 3 cases, the midgut had completely “vanished.” In the remaining 7 cases, the remnant midgut was surgically reduced into the abdominal cavity with care not to compromise the diminutive vascular pedicle. Abdominal exploration was performed several weeks later to reestablish bowel continuity; 4 required an ostomy and 2 underwent a serial transverse enteroplasty. Mean residual length of salvaged small bowel was 79 cm with retention of the distal half of the colon. Eight infants survived the initial hospitalization, with a mean length of stay of 121 days and mean hospital charge of $287,094. Six of the 7 long-term survivors have been completely weaned off total parenteral nutrition.A nihilistic attitude toward infants with closed gastroschisis may not be uniformly supported because in the majority of these infants’ long-term independence from total parenteral nutrition was achieved. Copyright © 2017 The Board of Regents of the University of Wisconsin System