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Authors Hudak K, Mazeh H, Sippel RS, Chen H
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Journal Am. J. Surg. Volume: 203 Issue: 3 Pages: 287-90; discussion 290-1
Publish Date 2012 Mar
PubMed ID 22264740

The aim of this study was to assess the malignancy rate in patients with Hürthle cell metaplasia (HCM) on fine-needle aspiration biopsy (FNAB).The pathology results of patients with benign colloid (BC) and HCM on FNAB were compared using a prospective database.One hundred fifty-three (65%) patients had BC on FNAB, and 82 (35%) had HCM. The mean nodule size was similar in both groups (25 ± 2 mm vs 26 mm ± 2 mm, P = .83). Malignancy was identified on the final pathology report in 21 (14%) versus 13 (16%) patients in the BC and HCM groups, respectively (P = .66). Of the patients with malignancy, the tumor was determined as microcarcinoma in 76% in the BC groups versus 85% in the HCM group (P = .48) and as incidental in 71% versus 85% (P = .39).A result of HCM on FNAB carries a similar rate of malignancy as BC and should not be treated differently. Most of the malignancies found were incidental microcarcinomas. Copyright © 2016 The Board of Regents of the University of Wisconsin System