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Authors Sippel RS, Chen H
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Journal Surg. Clin. North Am. Volume: 84 Issue: 3 Pages: 875-85
Publish Date 2004 Jun
PubMed ID 15145240

Up to 20% of patients with adrenal incidentalomas have abnormal cortisol production, and can be classified as having subclinical Cushing’s syndrome. Although these tumors do not secrete enough cortisol to lead to the development of overt Cushing’s syndrome, they are likely playing a contributory role in the development of hypertension, diabetes, osteoporosis, and obesity. Studies suggest that many of these problems can be reversed with surgical treatment. Additionally, if this diagnosis is not sought out before pursuing an adrenalectomy for an incidentaloma, the patient can develop profound postoperative adrenal insufficiency. Copyright © 2016 The Board of Regents of the University of Wisconsin System