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Authors Frasier LL, Greenberg CC, Neuman HB
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Journal Cancer Treat. Res. Volume: 164 Pages: 15-30
Publish Date 2015
PubMed ID 25677016

Breast cancer is the most commonly diagnosed cancer among women. To date, the use of efficacy randomized controlled trials (RCTs) in breast cancer have resulted in dramatic improvements in oncologic outcomes for this disease. However, not every question pertinent to breast cancer is amenable to such efficacy trials. This chapter will discuss some of the unique aspects of breast cancer that make efficacy RCTs challenging and/or impractical, how comparative effectiveness research can be used to address these issues, and identify several key questions which would benefit from ongoing comparative effectiveness research. Copyright © 2017 The Board of Regents of the University of Wisconsin System