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Authors Chen H, Kunnimalaiyaan M, Van Gompel JJ
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Journal Thyroid Volume: 15 Issue: 6 Pages: 511-21
Publish Date 2005 Jun
PubMed ID 16029117

Medullary thyroid cancer (MTC) is a prototypic neuroendocrine tumor of the thyroid C cells. Other than surgery, there are no curative therapies for MTC. In this review, we detail recent studies that suggest that targeting specific signaling pathways may be a viable strategy to control MTC tumor progression. Specifically, we discuss the role of the raf-1 and achaete-scute homologue-1 pathways in the MTC tumor growth and differentiation. Copyright © 2016 The Board of Regents of the University of Wisconsin System